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Midazolam determination by gas chromatography, liquid chromatography and gas chromatography--mass spectrometry
dc.contributor.authorVasiliades, Johnen_US
dc.contributor.authorSahawneh, Tuomahen_US
dc.date.accessioned2006-04-07T17:53:47Z
dc.date.available2006-04-07T17:53:47Z
dc.date.issued1982-03-12en_US
dc.identifier.citationVasiliades, John, Sahawneh, Tuomah (1982/03/12)."Midazolam determination by gas chromatography, liquid chromatography and gas chromatography--mass spectrometry." Journal of Chromatography B: Biomedical Sciences and Applications 228(): 195-203. <http://hdl.handle.net/2027.42/24035>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TG9-449TT2C-M/2/59607a3e2db869c01fa4c0d27e7de835en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24035
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6122692&dopt=citationen_US
dc.description.abstractMidazolam is determined in serum by gas chromatography with a nitrogen-selective detector, by liquid chromatography, and by gas chromatography--mass spectrometry. Comparable results are obtained with the three techniques with a within-run precision of 9% by gas chromatography and gas chromatography--mass spectrometry and 5% by liquid chromatography. Between-run precision is 13% by gas chromatography--mass spectrometry and 10% by liquid chromatography. Comparison of patient's sera by gas chromatography (x), liquid chromatography (y), and by gas chromatography (x), gas chromatography--mass spectrometry (y) gave correlations of 0.98 and 0.89, respectively. Interferences observed when using one technique, for example liquid chromatography, can be eliminated by analyzing the sample extract with one of the other techniques.en_US
dc.format.extent718789 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleMidazolam determination by gas chromatography, liquid chromatography and gas chromatography--mass spectrometryen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, The University of Michigan, Ann Arbor, MI 48109 U.S.A.en_US
dc.contributor.affiliationotherDepartment of Anesthesiology, University of Alabama in Birmingham, Birmingham, AL 35294 U.S.A.en_US
dc.identifier.pmid6122692en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24035/1/0000284.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0378-4347(00)80432-6en_US
dc.identifier.sourceJournal of Chromatography B: Biomedical Sciences and Applicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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