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Changes in the synthesis of exportable and nonexportable proteins in parotid glands during aging

dc.contributor.authorKim, Sun-Keeen_US
dc.contributor.authorCalkins, Debby W.en_US
dc.contributor.authorWeinhold, Paul A.en_US
dc.contributor.authorHan, Seong Sooen_US
dc.date.accessioned2006-04-07T17:54:06Z
dc.date.available2006-04-07T17:54:06Z
dc.date.issued1982-03en_US
dc.identifier.citationKim, Sun-Kee, Calkins, Debby W., Weinhold, Paul A., Han, Seong S. (1982/03)."Changes in the synthesis of exportable and nonexportable proteins in parotid glands during aging." Mechanisms of Ageing and Development 18(3): 239-250. <http://hdl.handle.net/2027.42/24045>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T31-47PG29K-7M/2/4c936cc8fa38ca71b6b4006deaaa74eeen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24045
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7087567&dopt=citationen_US
dc.description.abstractThe age-related differences in the synthesis of exportable and nonexportable proteins of the parotid salivary gland were compared in 2- and 24-month-old rats. Parotid slices from these rats were incubated in the presence of [14C]leucine and the amount of radioactivity incorporated into the water-soluble proteins of the postmicrosomal supernatant was compared. The exportable and nonexportable proteins were identified by electrophoretic separation of these proteins by comparing the banding patterns of the gel preparations from unstimulated glands to those from the glands stimulated to secrete. The radioactivity determination in various protein bands from these rats indicated that the synthesis of exportable secretory proteins declined with age, while that of nonexportable proteins did not appear to change.en_US
dc.format.extent676127 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleChanges in the synthesis of exportable and nonexportable proteins in parotid glands during agingen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeriatricsen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumResearch Service, V.A. Medical Center, Ann Arbor, Michigan 48105, U.S.A.;Department of Biochemistry, The University of Michigan Medical School, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationotherResearch Service, V.A. Medical Center, Ann Arbor, Michigan 48105, U.S.A.;Department of Anatomy, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Anatomy, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Anatomy, Ann Arbor, Michigan, U.S.A.en_US
dc.identifier.pmid7087567en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24045/1/0000294.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0047-6374(82)90113-0en_US
dc.identifier.sourceMechanisms of Ageing and Developmenten_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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