Responses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptide
dc.contributor.author | Wass, John A. | en_US |
dc.contributor.author | Varani, James | en_US |
dc.contributor.author | Piontek, Gerald E. | en_US |
dc.contributor.author | Ward, Peter A. | en_US |
dc.contributor.author | Orr, F. William | en_US |
dc.date.accessioned | 2006-04-07T17:59:16Z | |
dc.date.available | 2006-04-07T17:59:16Z | |
dc.date.issued | 1981-12 | en_US |
dc.identifier.citation | Wass, John A., Varani, James, Piontek, Gerald E., Ward, Peter A., Orr, F. William (1981/12)."Responses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptide." Cell Differentiation 10(6): 329-332. <http://hdl.handle.net/2027.42/24181> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B73GV-47PGYGB-7Y/2/53414a36b39c639399fa44d34b2170ca | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/24181 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7317948&dopt=citation | en_US |
dc.description.abstract | Two variant subpopulations of murine fibrosarcoma cells that differ significantly in their malignant potential and normal mouse fibroblasts were compared with regard to ability to respond chemotactically to collagen, collagen-derived peptides and the C5-derived tumor cell chemotactic peptide. Two distinct patterns of responsiveness were observed. The normal fibroblasts and non-metastasizing fibrosarcoma cells responded to the collagen products but not the C5 peptide. The metastasizing fibrosarcoma cells responded to the C5 peptide but not to the collagen products. These findings emphasize the similarities between the normal fibroblasts and the non-metastasizing fibrosarcoma cells. | en_US |
dc.format.extent | 281496 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Responses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptide | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Pathology, University of Manitoba Medical School, Winnipeg, Manitoba, Canada | en_US |
dc.identifier.pmid | 7317948 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/24181/1/0000440.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0045-6039(81)90024-5 | en_US |
dc.identifier.source | Cell Differentiation | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.