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Calcium-dependent action potentials in mouse spinal cord neurons in cell culture

dc.contributor.authorHeyer, Eric J.en_US
dc.contributor.authorMacdonald, Robert L.en_US
dc.contributor.authorBergey, Gregory K.en_US
dc.contributor.authorNelson, Phillip G.en_US
dc.date.accessioned2006-04-07T18:02:03Z
dc.date.available2006-04-07T18:02:03Z
dc.date.issued1981-09-14en_US
dc.identifier.citationHeyer, Eric J., Macdonald, Robert L., Bergey, Gregory K., Nelson, Phillip G. (1981/09/14)."Calcium-dependent action potentials in mouse spinal cord neurons in cell culture." Brain Research 220(2): 408-415. <http://hdl.handle.net/2027.42/24258>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6SYR-485CXJ6-3G/2/123f8cef03b7eb83981edc546d5bbdf4en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24258
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7284766&dopt=citationen_US
dc.description.abstractFollowing blockade of membrane potassium conductance with tetraethylammonium ions or 3-aminopyridine, long-duration action potentials were recorded from mouse spinal cord neurons in primary dissociated cell culture. The action potentials were calcium-dependent since they: (1) were not blocked by the sodium-channel blocker tetrodotoxin, (2) could be recorded in sodium-free, calcium-containing medium (3) could not be evoked in sodium-containing, calcium-free medium, (4) were blocked by calcium channel blockers manganese and cobalt and (5) had overshot amplitudes that varied linearly with the log of the extracellular calcium concentration (slope of 27.5 mV/decade change in calcium concentration).en_US
dc.format.extent543064 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleCalcium-dependent action potentials in mouse spinal cord neurons in cell cultureen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Neurology, University of Michigan Medical Center, Ann Arbor, Mich., U.S.A.en_US
dc.contributor.affiliationumDepartment of Neurology, University of Michigan Medical Center, Ann Arbor, Mich., U.S.A.en_US
dc.contributor.affiliationotherLaboratory of Developmental Neurobiology, National Institutes of Health, Bethesda, Md., U.S.A.en_US
dc.contributor.affiliationotherLaboratory of Developmental Neurobiology, National Institutes of Health, Bethesda, Md., U.S.A.en_US
dc.identifier.pmid7284766en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24258/1/0000521.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-8993(81)91234-8en_US
dc.identifier.sourceBrain Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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