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Ex vivo normothermic hemoperfusion of the canine pancreas: Applications and limitations of a modified experimental preparation
dc.contributor.authorEckhauser, Frederic E.en_US
dc.contributor.authorKnol, James A.en_US
dc.contributor.authorPorter-Fink, Vicki L.en_US
dc.contributor.authorLockery, D.en_US
dc.contributor.authorEdgcomb, Leslie P.en_US
dc.contributor.authorStrodel, William E.en_US
dc.contributor.authorWebb, Daviden_US
dc.contributor.authorSimmons, Jerry L.en_US
dc.date.accessioned2006-04-07T18:04:05Z
dc.date.available2006-04-07T18:04:05Z
dc.date.issued1981-07en_US
dc.identifier.citationEckhauser, Frederic, Knol, J. A., Porter-Fink, V., Lockery, D., Edgcomb, Leslie, Strodel, W. E., Webb, David, Simmons, Jerry (1981/07)."Ex vivo normothermic hemoperfusion of the canine pancreas: Applications and limitations of a modified experimental preparation." Journal of Surgical Research 31(1): 22-37. <http://hdl.handle.net/2027.42/24316>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WM6-4BNF4HK-2T6/2/c9fb139cfa7499dbe755b6aacf5bbb8aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24316
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7253638&dopt=citationen_US
dc.description.abstractEx vivo recirculation perfusion preparations of the canine pancreas are useful for the study of pancreatic physiology and exocrine secretory function. Vagaries of isolated ex vivo organ perfusion, however, require a thorough familiarity with available circulation media and component technology. Electrolyte and acid-base homeostasis can be facilitated by incorporating a dialysis unit into the perfusion circuit. Viability of the preparation is best assessed by constancy of vascular resistance and oxygen extraction during the period of perfusion. Limitations imposed by this closed method of organ perfusion on studies of pancreatic endocrine function and on duodenopancreatic hormonal interactions (enteroinsular axis) must be recognized.en_US
dc.format.extent2126726 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEx vivo normothermic hemoperfusion of the canine pancreas: Applications and limitations of a modified experimental preparationen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelSurgery and Anesthesiologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Surgery and Pathology Veterans Administration Medical Center, Ann Arbor, Michigan 48105, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid7253638en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24316/1/0000583.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-4804(81)90026-3en_US
dc.identifier.sourceJournal of Surgical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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