111In-8-hydroxyquinoline platelet labeling in dogs

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dc.contributor.author Porter-Fink, Vicki L. en_US
dc.contributor.author Eckhauser, Frederic E. en_US
dc.date.accessioned 2006-04-07T18:04:09Z
dc.date.available 2006-04-07T18:04:09Z
dc.date.issued 1981-07 en_US
dc.identifier.citation Porter-Fink, V. L., Eckhauser, Frederic E. (1981/07)."111In-8-hydroxyquinoline platelet labeling in dogs." Journal of Surgical Research 31(1): 87-92. <http://hdl.handle.net/2027.42/24318> en_US
dc.identifier.uri http://www.sciencedirect.com/science/article/B6WM6-4BNF4HK-2TG/2/e0fa1bdbc40eb0eecfb139fc9614e893 en_US
dc.identifier.uri http://hdl.handle.net/2027.42/24318
dc.identifier.uri http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6789007&dopt=citation en_US
dc.description.abstract This report validates a technique of separating and labeling canine platelets using indium-111-labeled 8-hydroxyquinoline (111In-8-HQ). Platelet survival time in six normal dogs was 6.3 +/- 0.7 (SD) days. Labeling efficiency using this technique was 51.8 +/- 9.2% (SEM) and elution loss of 111In-8-HQ label from platelets was consistently less than 4%. 111In label offers no observable advantages over the more traditional 51Cr label for platelet survival studies. However, the high efficiency labeling and -[gamma]-emission characteristics of 111In-8-HQ make it more suitable for non-invasive clot localization in patients with early pulmonary emboli and peripheral venous thrombi. en_US
dc.format.extent 475108 bytes
dc.format.extent 3118 bytes
dc.format.mimetype application/pdf
dc.format.mimetype text/plain
dc.language.iso en_US
dc.publisher Elsevier en_US
dc.title 111In-8-hydroxyquinoline platelet labeling in dogs en_US
dc.type Article en_US
dc.rights.robots IndexNoFollow en_US
dc.subject.hlbsecondlevel Surgery and Anesthesiology en_US
dc.subject.hlbtoplevel Health Sciences en_US
dc.description.peerreviewed Peer Reviewed en_US
dc.contributor.affiliationum University of Michigan Department of Surgery, Ann Arbor, Michigan 48109, USA; Veterans Administration Hospital, Department of Surgery, Ann Arbor, Michigan 48109, USA en_US
dc.contributor.affiliationum University of Michigan Department of Surgery, Ann Arbor, Michigan 48109, USA; Veterans Administration Hospital, Department of Surgery, Ann Arbor, Michigan 48109, USA en_US
dc.identifier.pmid 6789007 en_US
dc.description.bitstreamurl http://deepblue.lib.umich.edu/bitstream/2027.42/24318/1/0000585.pdf en_US
dc.identifier.doi http://dx.doi.org/10.1016/0022-4804(81)90034-2 en_US
dc.identifier.source Journal of Surgical Research en_US
dc.owningcollname Interdisciplinary and Peer-Reviewed
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