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111In-8-hydroxyquinoline platelet labeling in dogs
dc.contributor.authorPorter-Fink, Vicki L.en_US
dc.contributor.authorEckhauser, Frederic E.en_US
dc.date.accessioned2006-04-07T18:04:09Z
dc.date.available2006-04-07T18:04:09Z
dc.date.issued1981-07en_US
dc.identifier.citationPorter-Fink, V. L., Eckhauser, Frederic E. (1981/07)."111In-8-hydroxyquinoline platelet labeling in dogs." Journal of Surgical Research 31(1): 87-92. <http://hdl.handle.net/2027.42/24318>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WM6-4BNF4HK-2TG/2/e0fa1bdbc40eb0eecfb139fc9614e893en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24318
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6789007&dopt=citationen_US
dc.description.abstractThis report validates a technique of separating and labeling canine platelets using indium-111-labeled 8-hydroxyquinoline (111In-8-HQ). Platelet survival time in six normal dogs was 6.3 +/- 0.7 (SD) days. Labeling efficiency using this technique was 51.8 +/- 9.2% (SEM) and elution loss of 111In-8-HQ label from platelets was consistently less than 4%. 111In label offers no observable advantages over the more traditional 51Cr label for platelet survival studies. However, the high efficiency labeling and -[gamma]-emission characteristics of 111In-8-HQ make it more suitable for non-invasive clot localization in patients with early pulmonary emboli and peripheral venous thrombi.en_US
dc.format.extent475108 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.title111In-8-hydroxyquinoline platelet labeling in dogsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelSurgery and Anesthesiologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan Department of Surgery, Ann Arbor, Michigan 48109, USA; Veterans Administration Hospital, Department of Surgery, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumUniversity of Michigan Department of Surgery, Ann Arbor, Michigan 48109, USA; Veterans Administration Hospital, Department of Surgery, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid6789007en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24318/1/0000585.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-4804(81)90034-2en_US
dc.identifier.sourceJournal of Surgical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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