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Gonadectomy attenuates turning behavior produced by electrical stimulation of the nigrostriatal dopamine system in female but not male rats
dc.contributor.authorRobinson, Terry E.en_US
dc.contributor.authorCamp, Dianne M.en_US
dc.contributor.authorBecker, Jill B.en_US
dc.date.accessioned2006-04-07T18:06:16Z
dc.date.available2006-04-07T18:06:16Z
dc.date.issued1981-05-06en_US
dc.identifier.citationRobinson, Terry E., Camp, Dianne M., Becker, Jill B. (1981/05/06)."Gonadectomy attenuates turning behavior produced by electrical stimulation of the nigrostriatal dopamine system in female but not male rats." Neuroscience Letters 23(2): 203-208. <http://hdl.handle.net/2027.42/24376>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0G-485GHXB-H4/2/0073aafe898f9058bde08bbefc833ce8en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24376
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7254708&dopt=citationen_US
dc.description.abstractRotational behavior induced by electrical stimulation of ascending dopamine neurons is used as a behavioral model to investigate gender and hormonal influences on extra-hypothalamic dopamine systems. Steroid hormones influence the metabolism of many dopaminergic drugs, and therefore this approach avoids the complications inherent in drug-induced behavior models of dopamine activity. We found that gonadectomy of female, but not male, rats severely attenuates electrical stimulation-induced rotational behavior. This suggests that some female gonadal steroid hormone(s) may modulate the activity of ascending dopamine neurons, while male gonadal hormones do not.en_US
dc.format.extent846425 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleGonadectomy attenuates turning behavior produced by electrical stimulation of the nigrostriatal dopamine system in female but not male ratsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumno department foundPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumPsychology Department and Neuroscience Laboratory, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.identifier.pmid7254708en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24376/1/0000645.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0304-3940(81)90041-0en_US
dc.identifier.sourceNeuroscience Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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