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High-performance liquid chromatographic determination of penicillamine in whole blood, plasma, and urine
dc.contributor.authorBergstrom, Richard F.en_US
dc.contributor.authorKay, Donald R.en_US
dc.contributor.authorWagner, John G.en_US
dc.date.accessioned2006-04-07T18:08:10Z
dc.date.available2006-04-07T18:08:10Z
dc.date.issued1981-03-13en_US
dc.identifier.citationBergstrom, Richard F., Kay, Donald R., Wagner, John G. (1981/03/13)."High-performance liquid chromatographic determination of penicillamine in whole blood, plasma, and urine." Journal of Chromatography B: Biomedical Sciences and Applications 222(3): 445-452. <http://hdl.handle.net/2027.42/24427>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TG9-44BNN02-1D/2/0542638cd7a17d4488a15ee068fa4fbben_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24427
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7228952&dopt=citationen_US
dc.description.abstractA high-performance liquid chromatographic method for the determination of penicillamine in plasma, whole blood, and urine samples is described. The method uses a commercially available electrochemical detector at a potential of +0.1 V versus the Ag/AgCl reference electrode. This method is selective and sensitive for sulfhydryl compounds. The chromatography separates penicillamine from other endogenous sulfhydryl compounds with a limit of detection for penicillamine in biological samples of ca. 10-7 M.en_US
dc.format.extent647585 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleHigh-performance liquid chromatographic determination of penicillamine in whole blood, plasma, and urineen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUpjohn Center For Clinical Pharmacology and College of Pharmacy, The University of Michigan, Ann Arbor, MI 48109 U.S.A.en_US
dc.contributor.affiliationumUpjohn Center For Clinical Pharmacology and College of Pharmacy, The University of Michigan, Ann Arbor, MI 48109 U.S.A.en_US
dc.contributor.affiliationumUpjohn Center For Clinical Pharmacology and College of Pharmacy, The University of Michigan, Ann Arbor, MI 48109 U.S.A.en_US
dc.identifier.pmid7228952en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24427/1/0000698.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0378-4347(00)84145-6en_US
dc.identifier.sourceJournal of Chromatography B: Biomedical Sciences and Applicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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