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Somatostatin in human pancreatic and gastric juice
dc.contributor.authorArimura, A.en_US
dc.contributor.authorGroot, K.en_US
dc.contributor.authorTaminato, T.en_US
dc.contributor.authorErtan, A.en_US
dc.contributor.authorAkdamar, K.en_US
dc.contributor.authorRyan, J.en_US
dc.contributor.authorPienta, Kenneth J.en_US
dc.contributor.authorVinik, Aaron I.en_US
dc.date.accessioned2006-04-07T18:12:11Z
dc.date.available2006-04-07T18:12:11Z
dc.date.issued1981en_US
dc.identifier.citationArimura, A., Groot, K., Taminato, T., Ertan, A., Akdamar, K., Ryan, J., Pienta, K., Vinik, A. I. (1981)."Somatostatin in human pancreatic and gastric juice." Peptides 2(Supplement 2): 271-274. <http://hdl.handle.net/2027.42/24539>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0M-47STXDT-S6/2/620da69c81a578946bef3d5d0fbb7998en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24539
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6123989&dopt=citationen_US
dc.description.abstractConsiderable amounts of IRS are secreted after secretin injection in human pancreatic juice collected during endoscopic retrograde cholangiopancreatography. The mean IRS levels in the pancreatic juice of non-diabetic patients were 79+/-10 (SE) pg/ml. The IRS levels in NIDDM were considerably higher, the mean value being 1635+/-313 (SE) pg/ml. The mean IRS level in IDDM were 312+/-151 (SE) pg/ml. In IDDM, those patients whose blood glucose levels were well controlled by insulin showed low pancreatic juice IRS ranging from non-detectable to 46 pg/ml. On the other hand, those with uncontrolled hyperglycemia showed IRS levels ranging from 452 to 1047 pg/ml. Gel-filtration profiles of IRS in pancreatic juice extracts were not consistent in all cases. Some showed IRS peaks eluting with SS14 and SS28, while others contained IRS species that were eluted in more retarded fractions. The retarded IRS fraction exhibited biological activity indistinguishable from that of SS14 as indexed using a quantitative cytochemical method.en_US
dc.format.extent394996 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleSomatostatin in human pancreatic and gastric juiceen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USA;Department of Internal Medicine and Surgery, The University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USA;Department of Internal Medicine and Surgery, The University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationotherDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USAen_US
dc.contributor.affiliationotherDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USAen_US
dc.contributor.affiliationotherDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USAen_US
dc.contributor.affiliationotherDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USAen_US
dc.contributor.affiliationotherDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USAen_US
dc.contributor.affiliationotherDepartment of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; VA Medical Center, New Orleans, LA 70146, USAen_US
dc.identifier.pmid6123989en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24539/1/0000818.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0196-9781(81)90044-9en_US
dc.identifier.sourcePeptidesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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