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Phencyclidine-induced catalepsy in pigeons: Specificity and stereoselectivity
dc.contributor.authorKoek, Wouteren_US
dc.contributor.authorWoods, James H.en_US
dc.contributor.authorRice, Kenner C.en_US
dc.contributor.authorJacobson, Arthur E.en_US
dc.contributor.authorHuguenin, Philipp N.en_US
dc.contributor.authorBurke, Jr. , Terrence R.en_US
dc.date.accessioned2006-04-07T18:17:26Z
dc.date.available2006-04-07T18:17:26Z
dc.date.issued1984-11-27en_US
dc.identifier.citationKoek, Wouter, Woods, James H., Rice, Kenner C., Jacobson, Arthur E., Huguenin, Philipp N., Burke, Jr., Terrence R. (1984/11/27)."Phencyclidine-induced catalepsy in pigeons: Specificity and stereoselectivity." European Journal of Pharmacology 106(3): 635-638. <http://hdl.handle.net/2027.42/24637>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T1J-479DV9X-HG/2/b0177235a7faa6fbccc08cc00e6bf9a4en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24637
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6542865&dopt=citationen_US
dc.description.abstractA procedure is described for the rapid assessment of cataleptic activity (loss of righting, without head-drop and without eye closure) of phencyclidine-type drugs. Single- and cumulative-dosing procedures with phencyclidine and ketamine produced similar results. Pentobarbital produced loss of righting at doses which also induced head-drop and eye closure. Catalepsy was induced exclusively by the d-isomers of ketamine, 1-(1-phenylcyclohexyl)-3-methylpiperidine and [alpha]-dioxadrol. The procedure is suitable for studying compounds which may interact with phencyclidine receptors.en_US
dc.format.extent263979 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titlePhencyclidine-induced catalepsy in pigeons: Specificity and stereoselectivityen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan, Ann Arbor, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan, Ann Arbor, USA: Department of Psychology, University of Michigan, Ann Arbor, USAen_US
dc.contributor.affiliationotherDepartment of Laboratory of Chemistry, NIADDKD, NIH, Bethesda, Maryland, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Laboratory of Chemistry, NIADDKD, NIH, Bethesda, Maryland, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Laboratory of Chemistry, NIADDKD, NIH, Bethesda, Maryland, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Laboratory of Chemistry, NIADDKD, NIH, Bethesda, Maryland, U.S.A.en_US
dc.identifier.pmid6542865en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24637/1/0000048.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-2999(84)90070-0en_US
dc.identifier.sourceEuropean Journal of Pharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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