View Item 

Show simple item record

Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats
dc.contributor.authorGmerek, Debra E.en_US
dc.contributor.authorCowan, Alanen_US
dc.date.accessioned2006-04-07T18:17:56Z
dc.date.available2006-04-07T18:17:56Z
dc.date.issued1984-11en_US
dc.identifier.citationGmerek, Debra E., Cowan, Alan (1984/11)."Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats." Regulatory Peptides 9(4): 299-304. <http://hdl.handle.net/2027.42/24651>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0S-47V9FT6-8/2/47a5df7d71927cdc096ea38f2e72b08aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24651
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6522645&dopt=citationen_US
dc.description.abstractCentrally administered bombesin (0.1-3.5 [mu]g, i.c.v.) inhibits gastrointestinal transit of a charcoal meal in a dose-related manner in rats. The roles of pituitary and adrenal glands in the mediation of this effect were assessed. The inhibition of gastrointestinal transit associated with bombesin (0.5 [mu]g, i.c.v.) was prevented by either hypophysectomy or adrenalectomy. Bombesin-induced inhibition of gastrointestinal transit is therefore mediated through the pituitary-adrenal axis. This is in contrast to bombesin-induced scratching and inhibition of gastric acid secretion which are not markedly influenced by either hypophysectomy or adrenalectomy.en_US
dc.format.extent308501 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titlePituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in ratsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Pharmacology, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A.en_US
dc.identifier.pmid6522645en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24651/1/0000064.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0167-0115(84)90082-Xen_US
dc.identifier.sourceRegulatory Peptidesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
0000064.pdf
Size:
301.2KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.