Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats
dc.contributor.author | Gmerek, Debra E. | en_US |
dc.contributor.author | Cowan, Alan | en_US |
dc.date.accessioned | 2006-04-07T18:17:56Z | |
dc.date.available | 2006-04-07T18:17:56Z | |
dc.date.issued | 1984-11 | en_US |
dc.identifier.citation | Gmerek, Debra E., Cowan, Alan (1984/11)."Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats." Regulatory Peptides 9(4): 299-304. <http://hdl.handle.net/2027.42/24651> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T0S-47V9FT6-8/2/47a5df7d71927cdc096ea38f2e72b08a | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/24651 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6522645&dopt=citation | en_US |
dc.description.abstract | Centrally administered bombesin (0.1-3.5 [mu]g, i.c.v.) inhibits gastrointestinal transit of a charcoal meal in a dose-related manner in rats. The roles of pituitary and adrenal glands in the mediation of this effect were assessed. The inhibition of gastrointestinal transit associated with bombesin (0.5 [mu]g, i.c.v.) was prevented by either hypophysectomy or adrenalectomy. Bombesin-induced inhibition of gastrointestinal transit is therefore mediated through the pituitary-adrenal axis. This is in contrast to bombesin-induced scratching and inhibition of gastric acid secretion which are not markedly influenced by either hypophysectomy or adrenalectomy. | en_US |
dc.format.extent | 308501 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A. | en_US |
dc.identifier.pmid | 6522645 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/24651/1/0000064.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0167-0115(84)90082-X | en_US |
dc.identifier.source | Regulatory Peptides | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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