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Quantitative autoradiography of [3H]sulpiride binding sites in rat brain

dc.contributor.authorJastrow, Therese Ryanen_US
dc.contributor.authorRichfield, Eric K.en_US
dc.contributor.authorGnegy, Margaret E.en_US
dc.date.accessioned2006-04-07T18:19:30Z
dc.date.available2006-04-07T18:19:30Z
dc.date.issued1984-09-28en_US
dc.identifier.citationJastrow, Therese Ryan, Richfield, Eric, Gnegy, Margaret E. (1984/09/28)."Quantitative autoradiography of [3H]sulpiride binding sites in rat brain." Neuroscience Letters 51(1): 47-53. <http://hdl.handle.net/2027.42/24695>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0G-485YF91-DK/2/ce6d857fb809a5e2a86bb1868c579caben_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24695
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6083509&dopt=citationen_US
dc.description.abstractA technique has been developed to investigate [3H]sulpiride binding in rat brain sections using quantitative autoradiography and tritium-sensitive film. Binding was saturable and reversible with very low nonspecific binding. [3H]Sulpiride bound to an apparent single population of sites in striatum with a Kd of 3.2 nM and Bmax of 447 fmol/mg protein. Binding sites were localized in the lamina glomerulosa of the olfactory bulb, nucleus accumbens, olfactory tubercle, striatum and substantia nigra.en_US
dc.format.extent592160 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleQuantitative autoradiography of [3H]sulpiride binding sites in rat brainen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, Department of Pharmacology, M6322 Medical Science I Building, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumUniversity of Michigan, Department of Neurology, Neuroscience Lab Building, Ann Arbor MI, 48109, U.S.A.en_US
dc.contributor.affiliationumUniversity of Michigan, Department of Pharmacology, M6322 Medical Science I Building, Ann Arbor, MI 48109, U.S.A.en_US
dc.identifier.pmid6083509en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24695/1/0000114.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0304-3940(84)90261-1en_US
dc.identifier.sourceNeuroscience Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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