Effects of kainic acid and radiofrequency lesions of the pulvinar on visual discrimination in the monkey
dc.contributor.author | Nagel-Leiby, Sandra | en_US |
dc.contributor.author | Bender, D. B. | en_US |
dc.contributor.author | Butter, Charles M. | en_US |
dc.date.accessioned | 2006-04-07T18:27:55Z | |
dc.date.available | 2006-04-07T18:27:55Z | |
dc.date.issued | 1984-05-23 | en_US |
dc.identifier.citation | Nagel-Leiby, Sandra, Bender, D. B., Butter, Charles M. (1984/05/23)."Effects of kainic acid and radiofrequency lesions of the pulvinar on visual discrimination in the monkey." Brain Research 300(2): 295-303. <http://hdl.handle.net/2027.42/24814> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYR-4840R1S-22K/2/02558dd23badec1ded0e62347b3fc2fd | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/24814 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6733475&dopt=citation | en_US |
dc.description.abstract | Monkeys with thermocoagulation or kainic acid lesions of the pulvinar and unoperated control monkeys were tested in two tasks: pattern discrimination retention and color discrimination learning in which the stimuli were located at the response sites or were separated spatially from them (S-R separation). The monkeys with kainic acid pulvinar lesions were mildly impaired in retention of the pattern discrimination, but were unimpaired in the color discrimination tasks with or without the S-R separation. The monkeys with thermocoagulation lesions, like monkeys with superior colliculus lesions in a prior study, were severely impaired in performing one of the color discrimination tasks with S-R separation. These findings suggest that: (a) the inferior pulvinar, unlike the superior colliculus, does not contribute to the performance of discriminations involving S-R separation; and (b) corticotectal projections traversing the pulvinar and destroyed by the thermocoagulation lesions are crucial to the performance of discriminations involving S-R separation. The results of an earlier experiment also suggested that interruption of corticotectal fibers passing through the pulvinar impairs performance in another task sensitive to superior colliculus lesions -- spatial localization of light flashes. Thus, corticotectal projections may be crucial for the contribution of the colliculus to performance in a variety of visual tasks. | en_US |
dc.format.extent | 683394 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Effects of kainic acid and radiofrequency lesions of the pulvinar on visual discrimination in the monkey | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Neuroscience Laboratory and Psychology Department, The University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Neuroscience Laboratory and Psychology Department, The University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationother | Division of Neurobiology, Physiology Department, State University of New York, Buffalo, NY 14226, U.S.A. | en_US |
dc.identifier.pmid | 6733475 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/24814/1/0000240.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0006-8993(84)90839-4 | en_US |
dc.identifier.source | Brain Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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