Novel inhibition of carbonic anhydrase isozymes I, II and III by carbamoyl phosphate
dc.contributor.author | Carter, Nicholas D. | en_US |
dc.contributor.author | Chegwidden, W. Richard | en_US |
dc.contributor.author | Hewett-Emmett, David | en_US |
dc.contributor.author | Jeffery, S. | en_US |
dc.contributor.author | Shiels, A. | en_US |
dc.contributor.author | Tashian, Richard E. | en_US |
dc.date.accessioned | 2006-04-07T18:32:10Z | |
dc.date.available | 2006-04-07T18:32:10Z | |
dc.date.issued | 1984-01-09 | en_US |
dc.identifier.citation | Carter, N. D., Chegwidden, W. R., Hewett-Emmett, D., Jeffery, S., Shiels, A., Tashian, R. E. (1984/01/09)."Novel inhibition of carbonic anhydrase isozymes I, II and III by carbamoyl phosphate." FEBS Letters 165(2): 197-200. <http://hdl.handle.net/2027.42/24933> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T36-44DT20D-HM/2/eee3a084163dc1c792b777d97def1a8c | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/24933 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6420187&dopt=citation | en_US |
dc.description.abstract | Carbamoyl phosphate has been shown to inhibit carbonic anhydrase (CA) isozymes CA I, CA II and CA III. This physiologically important molecule is the most potent, naturally occurring inhibitor of carbonic anhydrase yet found. It is also unique, among carbonic anhydrase inhibitors discovered hitherto, in that it inhibits the 3 isozymes with equal effect, despite their strikingly different properties. The results imply the participation of carbonic anhydrase in the regulation of substrate availability for the urea cycle. | en_US |
dc.format.extent | 441677 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Novel inhibition of carbonic anhydrase isozymes I, II and III by carbamoyl phosphate | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Biological Sciences, Sheffield City Polytechnic, Sheffield S1 1WB England. | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationother | Department of Child Health, St. George's Hospital Medical School, London SW17 ORE, England | en_US |
dc.contributor.affiliationother | Department of Child Health, St. George's Hospital Medical School, London SW17 ORE, England | en_US |
dc.contributor.affiliationother | Department of Child Health, St. George's Hospital Medical School, London SW17 ORE, England | en_US |
dc.identifier.pmid | 6420187 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/24933/1/0000360.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0014-5793(84)80168-4 | en_US |
dc.identifier.source | FEBS Letters | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.