Development of the catecholamine innervation of the supraoptic nucleus in the Brattleboro rat
dc.contributor.author | Sladek, Jr. , John R. | en_US |
dc.contributor.author | Fields, Julie | en_US |
dc.contributor.author | Phelps, Carol J. | en_US |
dc.contributor.author | Khachaturian, Henry | en_US |
dc.date.accessioned | 2006-04-07T18:33:39Z | |
dc.date.available | 2006-04-07T18:33:39Z | |
dc.date.issued | 1984 | en_US |
dc.identifier.citation | Sladek, Jr., John R., Fields, Julie, Phelps, Carol J., Khachaturian, Henry (1984)."Development of the catecholamine innervation of the supraoptic nucleus in the Brattleboro rat." Peptides 5(Supplement 1): 151-155. <http://hdl.handle.net/2027.42/24975> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T0M-47T2M43-2S/2/f0d879f8e17f04e43c8ad5a109c428f8 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/24975 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6483652&dopt=citation | en_US |
dc.description.abstract | The ontogenetic development of the noradrenergic innervation of the supraoptic nucleus was studied in the Brattleboro rat at late postcoital and early postnatal ages. This genetic mutant offers a useful model for analysis of neuronal development because of the absence of a specific peptide component of identifiable target neurons and has been used presently to eliminate the possibility that such substances are essential for the establishment of normal connectivity during postnatal development. In this model, catecholamine varicosities were seen in juxtaposition to vasopressin-deficient perikarya during the initial phases of postnatal development, but these varicosities gradually decreased in number suggesting the possibility that the target neuron peptide, or some functional aspect of the neuron, may be necessary for the normal maintenance of this neuronal interaction. | en_US |
dc.format.extent | 404256 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Development of the catecholamine innervation of the supraoptic nucleus in the Brattleboro rat | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Rochester School of Medicine, Rochester, NY 14642, USA; Center for Brain Research, University of Rochester School of Medicine, Rochester, NY 14642, USA; Mental Health Research Institute, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Rochester School of Medicine, Rochester, NY 14642, USA; Center for Brain Research, University of Rochester School of Medicine, Rochester, NY 14642, USA; Mental Health Research Institute, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Rochester School of Medicine, Rochester, NY 14642, USA; Center for Brain Research, University of Rochester School of Medicine, Rochester, NY 14642, USA; Mental Health Research Institute, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Rochester School of Medicine, Rochester, NY 14642, USA; Center for Brain Research, University of Rochester School of Medicine, Rochester, NY 14642, USA; Mental Health Research Institute, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA | en_US |
dc.identifier.pmid | 6483652 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/24975/1/0000402.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0196-9781(84)90273-0 | en_US |
dc.identifier.source | Peptides | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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