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Lead activates calmodulin sensitive processes
dc.contributor.authorGoldstein, Gary W.en_US
dc.contributor.authorAr, Dianeen_US
dc.date.accessioned2006-04-07T18:38:43Z
dc.date.available2006-04-07T18:38:43Z
dc.date.issued1983-09-05en_US
dc.identifier.citationGoldstein, Gary W., Ar, Diane (1983/09/05)."Lead activates calmodulin sensitive processes." Life Sciences 33(10): 1001-1006. <http://hdl.handle.net/2027.42/25113>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T99-4779C6D-1G9/2/b4a82fe903bc061bcf1a2642a190b86aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25113
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6310286&dopt=citationen_US
dc.description.abstractThe effect of lead on two calcium sensitive processes was determined. Micromolar concentrations of lead successfully replaced calcium in the activation of calmodulin-sensitive phosphodiesterase and in the promotion of potassium loss from erythrocytes. Both actions of lead were blocked by trifluoperazine--an inhibitor of calmodulin function. We propose that some of the toxic effects of lead may be explained by its interaction with calmodulin.en_US
dc.format.extent278389 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleLead activates calmodulin sensitive processesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Pediatrics and Neurology University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Pediatrics and Neurology University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid6310286en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25113/1/0000546.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0024-3205(83)90757-9en_US
dc.identifier.sourceLife Sciencesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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