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Ca2+, histamine antagonists and relaxation to electrical impulses in dog coronary artery
dc.contributor.authorGantzos, Robin D.en_US
dc.contributor.authorEbeigbe, Anthony B.en_US
dc.contributor.authorClinton Webb, R.en_US
dc.date.accessioned2006-04-07T18:42:37Z
dc.date.available2006-04-07T18:42:37Z
dc.date.issued1983-05-06en_US
dc.identifier.citationGantzos, Robin D., Ebeigbe, Anthony B., Clinton Webb, R. (1983/05/06)."Ca2+, histamine antagonists and relaxation to electrical impulses in dog coronary artery." European Journal of Pharmacology 89(3-4): 287-291. <http://hdl.handle.net/2027.42/25219>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T1J-47463BT-5B/2/ad554db8bc7161e9c3ae2a8f38ea7a50en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25219
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6873165&dopt=citationen_US
dc.description.abstractIsolated dog coronary arteries relax in response to electrical stimulation (0.1-8.0 Hz, 9 V, 1.0 ms) following contraction induced by serotonin. Cimetidine, metiamide and ranitidine inhibited this relaxation. The relaxation was not blocked by pyrilamine. Reducing the concentration of Ca+ (0.1 mM) decreased the rate of relaxation whereas relaxation was more rapid when the Ca2+ concentration was increased (3.2 mM). These results suggest that relaxation to electrical stimulation is modulated by Ca2+ and by the H2-subclass of histamine receptors.en_US
dc.format.extent350465 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleCa2+, histamine antagonists and relaxation to electrical impulses in dog coronary arteryen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Physiology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Physiology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Physiology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A.en_US
dc.identifier.pmid6873165en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25219/1/0000659.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-2999(83)90508-3en_US
dc.identifier.sourceEuropean Journal of Pharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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