Separation of subtypes of depression using discriminant analysis : Separation of bipolar endogenous depression from nonendogenous ("Neurotic") depression
dc.contributor.author | Feinberg, Michael | en_US |
dc.contributor.author | Carroll, Bernard J. | en_US |
dc.date.accessioned | 2006-04-07T18:42:53Z | |
dc.date.available | 2006-04-07T18:42:53Z | |
dc.date.issued | 1983-05 | en_US |
dc.identifier.citation | Feinberg, Michael, Carroll, Bernard J. (1983/05)."Separation of subtypes of depression using discriminant analysis : Separation of bipolar endogenous depression from nonendogenous ("Neurotic") depression." Journal of Affective Disorders 5(2): 129-139. <http://hdl.handle.net/2027.42/25226> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T2X-45RCCB2-5M/2/6fab44ccf8baef55314181527765d641 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25226 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6222092&dopt=citation | en_US |
dc.description.abstract | We derived a discriminant function separating patients with bipolar endogenous depression ("melancholia") from patients with nonendogenous ("neurotic") depression, and showed that the difference between the groups was not one of overall severity of illness alone. The discriminant function (DF) included 5 clinical items.We reduced the DF to a discriminant index (DI) with integral item weights, and trichotomized the DI scores into two definite classifications and an intermediate, uncertain classification. We cross-validated this DI in a separate group of patients, and found no decrease in the accuracy of classification on cross-validation. Thirty-three of 41 (80%) of the patients in the cross-validation group were classified by the DI; 26 of 33 (79%) correctly.We also validated the DI classification against an external, biological marker, the dexamethasone suppression test (DST). The DI predicted the DST result with the same accuracy as the clinical diagnoses did, supporting the validity of the DI. | en_US |
dc.format.extent | 459108 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Separation of subtypes of depression using discriminant analysis : Separation of bipolar endogenous depression from nonendogenous ("Neurotic") depression | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychology | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Psychiatry and Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Psychiatry and Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.identifier.pmid | 6222092 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25226/1/0000667.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0165-0327(83)90005-8 | en_US |
dc.identifier.source | Journal of Affective Disorders | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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