[omega]-Difluoroamino carboxylic acids: Readily accessible fluorine-labeled fatty acid analogs
dc.contributor.author | Jewett, Douglas M. | en_US |
dc.contributor.author | Ehrenkaufer, Richard E. | en_US |
dc.date.accessioned | 2006-04-07T18:43:10Z | |
dc.date.available | 2006-04-07T18:43:10Z | |
dc.date.issued | 1983-05 | en_US |
dc.identifier.citation | Jewett, D. M., Ehrenkaufer, R. E. (1983/05)."[omega]-Difluoroamino carboxylic acids: Readily accessible fluorine-labeled fatty acid analogs." Journal of Fluorine Chemistry 22(5): 475-481. <http://hdl.handle.net/2027.42/25234> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TGD-42GF5M5-38/2/33d7760d0da7fa86a687601786cbbce2 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25234 | |
dc.description.abstract | 15-Difluoroamino-pentadecanoic acid and 12-difluoroamino-dodecanoic acid were prepared by treating the corresponding lactams with F2 in aqueous acetonitrile. The intermediate N-fluorolactams were also isolated. Whereas isolated -CH2---F groups introduce considerable polarity into aliphatic chains, -CH2---NF2 groups did not. The -NF2 group thus appears to be a suitable isostere of the -CH3 group, where introduction of a 18F label is required for positron-based or 19F NMR imaging. | en_US |
dc.format.extent | 300534 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | [omega]-Difluoroamino carboxylic acids: Readily accessible fluorine-labeled fatty acid analogs | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Cyclotron/PET Facility, University of Michigan Medical Center, Box 056, Ann Arbor, Michigan 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Cyclotron/PET Facility, University of Michigan Medical Center, Box 056, Ann Arbor, Michigan 48109, U.S.A. | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25234/1/0000676.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/S0022-1139(00)81168-9 | en_US |
dc.identifier.source | Journal of Fluorine Chemistry | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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