In vitro characterization of an avian reovirus vaccine strain
dc.contributor.author | Gouvea, Vera | en_US |
dc.contributor.author | Huang, Diana D. | en_US |
dc.contributor.author | Ramos, Teresa | en_US |
dc.contributor.author | Schnitzer, Thomas J. | en_US |
dc.date.accessioned | 2006-04-07T18:43:26Z | |
dc.date.available | 2006-04-07T18:43:26Z | |
dc.date.issued | 1983-04-15 | en_US |
dc.identifier.citation | Gouvea, Vera, Huang, Diana D., Ramos, Teresa, Schnitzer, Thomas J. (1983/04/15)."In vitro characterization of an avian reovirus vaccine strain." Virology 126(1): 240-247. <http://hdl.handle.net/2027.42/25241> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WXR-4C546Y3-M/2/aa0e4e7fb0264422d83d206ed3ae49ca | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25241 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6845656&dopt=citation | en_US |
dc.description.abstract | In vitro studies were performed to characterize the vaccine strain, designated P100, derived from the arthrogenic reovirus isolate, S1133, by vold adaptation. P100 appeared to be temperature sensitive, shown by a marked drop in titer and efficiency of plaquing after incubation at 41[deg]. Studies indicated that genomic double-stranded RNA and protein synthesis were severely restricted at the elevated temperature. Differences in the growth behavior of P100 and S1133 at 37[deg] were also noted. The vaccine strain seemed to be more cell associated than S1133. Three outer coat proteins of P100 grown at 37[deg] displayed mobilities different from those of S1133 by PAGE. It is possible that alterations in these proteins may have some relationship to the growth characteristics observed for the P100 strain. | en_US |
dc.format.extent | 1817928 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | In vitro characterization of an avian reovirus vaccine strain | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Rackham Arthritis Research Unit, Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Rackham Arthritis Research Unit, Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA; Rackham Arthritis Research Unit, Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.identifier.pmid | 6845656 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25241/1/0000683.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0042-6822(83)90475-0 | en_US |
dc.identifier.source | Virology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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