Visual and auditory anomalies in Chediak-Higashi syndrome
dc.contributor.author | Creel, Donnell | en_US |
dc.contributor.author | Boxer, Laurence A. | en_US |
dc.contributor.author | Fauci, Anthony S. | en_US |
dc.date.accessioned | 2006-04-07T18:44:53Z | |
dc.date.available | 2006-04-07T18:44:53Z | |
dc.date.issued | 1983-03 | en_US |
dc.identifier.citation | Creel, Donnell, Boxer, Laurence A., Fauci, Anthony S. (1983/03)."Visual and auditory anomalies in Chediak-Higashi syndrome." Electroencephalography and Clinical Neurophysiology 55(3): 252-257. <http://hdl.handle.net/2027.42/25282> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYX-482YXFJ-9W/2/b677a6c2431981bf4a51c72c1cbaffbe | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25282 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6186456&dopt=citation | en_US |
dc.description.abstract | Albinism is correlated with misrouting of decussating retinal fibers in the brain. There is also evidence of anomalies of decussating auditory pathways in albinos. The Chediak-Higashi syndrome (CHS) is a rare form of partial albinism which includes increased susceptibility to infections, a hemorrhagic tendency and peripheral polyneuropathies. Binocular and monocular pattern-onset visually evoked potentials (VEPs) and monaural auditory brain stem responses (ABRs) were recorded from 4 subjects with CHS. Three of the CHS demonstrated asymmetric monocular VEPs and failed the Titmus stereovision test. All 4 CHS produced asymmetric ABRs similar to those reported for albinos. Although the hair, skin and irises are relatively well pigmented in CHS, these individuals apparently have anomalies of their central visual and auditory pathways. | en_US |
dc.format.extent | 426420 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Visual and auditory anomalies in Chediak-Higashi syndrome | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pediatric Hematology, School of Medicine, University of Michigan, Ann Arbor, Mich. 48109, U.S.A. | en_US |
dc.contributor.affiliationother | Veterans Administration Medical Center, and Department of Ophthalmology, University of Utah, Salt Lake City, Utah 84148, U.S.A. | en_US |
dc.contributor.affiliationother | National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. 20205, U.S.A. | en_US |
dc.identifier.pmid | 6186456 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25282/1/0000725.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0013-4694(83)90202-X | en_US |
dc.identifier.source | Electroencephalography and Clinical Neurophysiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.