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Muscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neurons

dc.contributor.authorNowak, Linda M.en_US
dc.contributor.authorMacdonald, Robert L.en_US
dc.date.accessioned2006-04-07T18:46:11Z
dc.date.available2006-04-07T18:46:11Z
dc.date.issued1983-01-31en_US
dc.identifier.citationNowak, Linda M., Macdonald, Robert L. (1983/01/31)."Muscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neurons." Neuroscience Letters 35(1): 85-91. <http://hdl.handle.net/2027.42/25316>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0G-485H7BV-11M/2/0d7507cd4535583d7c9c24b686a4be61en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25316
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6843894&dopt=citationen_US
dc.description.abstractMuscarine produced membrane depolarization and decreased membrane conductance of mouse spinal cord neurons in dissociated cell culture. When the neurons were voltage clamped, muscarine evoked inward currents which increased with membrane depolarization and decreased with membrane hyperpolarization. However, the muscarine-induced inward currents did not invert at large negative potentials, suggesting that muscarine decreased a voltage-dependent potassium current (m-current) [2]. Using the voltage-jump current-relaxation technique, m-current was demonstrated in spinal cord neurons and shown to be a muscarine-sensitive potassium current.en_US
dc.format.extent403629 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleMuscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neuronsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Neurology, The University of Michigan, Ann Arbor, MI, U.S.A.en_US
dc.contributor.affiliationumDepartment of Neurology, The University of Michigan, Ann Arbor, MI, U.S.A.en_US
dc.identifier.pmid6843894en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25316/1/0000761.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0304-3940(83)90531-1en_US
dc.identifier.sourceNeuroscience Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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