Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary
dc.contributor.author | Alessi, Norman E. | en_US |
dc.contributor.author | Khachaturian, Henry | en_US |
dc.contributor.author | Watson, Stanley J. | en_US |
dc.contributor.author | Akil, Huda | en_US |
dc.date.accessioned | 2006-04-07T18:47:51Z | |
dc.date.available | 2006-04-07T18:47:51Z | |
dc.date.issued | 1983 | en_US |
dc.identifier.citation | Alessi, Norman E., Khachaturian, Henry, Watson, Stanley, Akil, Huda (1983)."Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary." Life Sciences 33(Supplement 1): 57-60. <http://hdl.handle.net/2027.42/25358> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T99-4754CDX-1GC/2/8679a783ed208b27a02005f9d85fee64 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25358 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6319911&dopt=citation | en_US |
dc.description.abstract | Extracts of the anterior lobe and intermediate lobe of postnatal (P) (Day P1, P7, P14, P21, P28, P35, P42) and adult male Spraque-Dawley rats were analyzed by both a Beta-endorphin (B-END) radioimmunoassay and a radioimmunoassay for N-acetyl-B-END. In the anterior lobe, on P1, less than 2% of the adult level of B-END was present. By P42 this level had increased to 21% of adult levels. In the intermediate lobe, on P1, the B-END levels were less than 0.1% of the adult level, and by P42 this level approached approximately 45% of the adult levels. N-acetylated B-END was identified in both anterior lobe and intermediate lobe from P1 through adulthood. In the anterior lobe at P1, N-acetyl-B-END immunoreactivity contributes approximately 25% of the total B-END immunoreactivity. This level drops to less than 10% by P21, and to adult-like levels by P42 (less than 5%). On the other hand, in the intermediate lobe, the N-acetyl-B-END levels start at 70% of the total B-END immunoreactivity at P1 and by P14 reaches adult-like proportions of 90% or more of the total B-END immunoreactive material. | en_US |
dc.format.extent | 215753 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.identifier.pmid | 6319911 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25358/1/0000805.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0024-3205(83)90443-5 | en_US |
dc.identifier.source | Life Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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