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[3H] dynorphin binding to guinea pig and rat brain
dc.contributor.authorYoung, Elizabeth A.en_US
dc.contributor.authorWalker, J. Michaelen_US
dc.contributor.authorHoughten, Richard A.en_US
dc.contributor.authorAkil, Hudaen_US
dc.date.accessioned2006-04-07T18:49:20Z
dc.date.available2006-04-07T18:49:20Z
dc.date.issued1983en_US
dc.identifier.citationYoung, E., Walker, J. M., Houghten, R., Akil, H. (1983)."[3H] dynorphin binding to guinea pig and rat brain." Life Sciences 33(Supplement 1): 287-290. <http://hdl.handle.net/2027.42/25400>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T99-4754CDX-1JC/2/0bc77f6d63c03715a2c4e54f6420700een_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25400
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6141490&dopt=citationen_US
dc.description.abstract[3H] Dynorphin can be shown to bind to the brains of both rat and guinea pigs with approximately 50% specific binding. Characterization of the binding in terms of multiple opiate receptor types supports the kappa selectivity of dynorphin in guinea pig. However, in rat brain, a substantial proportion of the [3H] dynorphin binding is displaced by morphine, suggesting a mu as well as kappa component. Consequently, in rat, dynorphin may show effects at both mu and kappa receptors .en_US
dc.format.extent205260 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.title[3H] dynorphin binding to guinea pig and rat brainen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid6141490en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25400/1/0000849.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0024-3205(83)90499-Xen_US
dc.identifier.sourceLife Sciencesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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