Heredity, stress and blood pressure, a family set approach: The Detroit Project revisited,
dc.contributor.author | Moll, Patricia Peyser | en_US |
dc.contributor.author | Harburg, Ernest | en_US |
dc.contributor.author | Burns, Trudy L. | en_US |
dc.contributor.author | Schork, M. Anthony | en_US |
dc.contributor.author | Ozgoren, F. | en_US |
dc.date.accessioned | 2006-04-07T18:49:39Z | |
dc.date.available | 2006-04-07T18:49:39Z | |
dc.date.issued | 1983 | en_US |
dc.identifier.citation | Moll, P. P., Harburg, E., Burns, T. L., Schork, M. A., Ozgoren, F. (1983)."Heredity, stress and blood pressure, a family set approach: The Detroit Project revisited,." Journal of Chronic Diseases 36(4): 317-328. <http://hdl.handle.net/2027.42/25409> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B7GH4-4C11DVR-72/2/1df8e2e960e615630843376bf54651bd | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25409 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6833451&dopt=citation | en_US |
dc.description.abstract | Earlier conclusions from the Detroit Project utilizing an innovative "family sets" approach indicated that unspecified environmental factors, rather than genes, are the main determinants of blood pressure variation in blacks and whites. We report new estimates of the fraction of variation in blood pressure associated with genetic differences among individuals obtained under two methodologies: the method originally proposed for family sets and a maximum likelihood method. The family sets estimates of heritability were significant for systolic and diastolic blood pressure in both blacks and whites. Estimates for both the likelihood analysis and family sets method are within the range of estimates reported in other studies. In the present study all sets collected were included, the sets were stratified only by race and a different estimate of variance for the family sets estimate of heritability was used. The discrepancies between results presented here and the original study are attributed to these three factors. | en_US |
dc.format.extent | 1117548 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Heredity, stress and blood pressure, a family set approach: The Detroit Project revisited, | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, U.S.A.; Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Psychology, University of Michigan, Ann Arbor, MI 48109, U.S.A.; Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Psychology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.identifier.pmid | 6833451 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25409/1/0000858.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0021-9681(83)90117-0 | en_US |
dc.identifier.source | Journal of Chronic Diseases | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.