Noninvasive quantification of jeopardized myocardial mass in dogs using 2-dimensional echocardiography and thallium-201 tomography
dc.contributor.author | Weiss, Robert J. | en_US |
dc.contributor.author | Buda, Andrew J. | en_US |
dc.contributor.author | Pasyk, Stanislaw | en_US |
dc.contributor.author | O'Neill, William W. | en_US |
dc.contributor.author | Keyes, Jr. , John W. | en_US |
dc.contributor.author | Pitt, Bertram | en_US |
dc.date.accessioned | 2006-04-07T18:51:06Z | |
dc.date.available | 2006-04-07T18:51:06Z | |
dc.date.issued | 1983-12-01 | en_US |
dc.identifier.citation | Weiss, Robert J., Buda, Andrew J., Pasyk, Stanislaw, O'Neill, William W., Keyes, Jr., John W., Pitt, Bertram (1983/12/01)."Noninvasive quantification of jeopardized myocardial mass in dogs using 2-dimensional echocardiography and thallium-201 tomography." The American Journal of Cardiology 52(10): 1340-1344. <http://hdl.handle.net/2027.42/25450> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T10-4C7V5X7-1W5/2/d39b00e47b26b28d87779bce56584ded | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25450 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6606353&dopt=citation | en_US |
dc.description.abstract | The evaluation of jeopardized myocardial mass is important in defining the effect of interventions during myocardial infarction. To quantitate the in vivo mass at risk, 2-dimensional echocardiography (2-D echo) and thallium-201 single-photon emission computed tomography (SPECT) was performed in 10 closed-chest dogs after circumflex coronary artery occlusion. The 2-D images were manually digitized to compute left ventricular (LV) mass using a modified Simpson's rule algorithm. This measure of LV mass correlated well with the actual LV mass (r = 0.97). Perfused myocardial mass was estimated from thallium SPECT images 4 hours after occlusion using a region-growing algorithm. After the dogs were killed, the jeopardized mass was outlined using a dual perfusion staining technique using triphenyltetrazolium chloride and Evans blue dye. The actual perfused mass was well estimated by the thallium images (r = 0.96). The noninvasively determined mass at risk was calculated as: 2-D mass -- thallium SPECT mass, and correlated well with the pathologically determined mass at risk (r = 0.91). Thus, the jeopardized mass may be determined noninvasively by using 2-D echo and thallium-201 tomography. This approach may provide further information regarding the effect of intervention therapy on jeopardized myocardium. | en_US |
dc.format.extent | 698177 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Noninvasive quantification of jeopardized myocardial mass in dogs using 2-dimensional echocardiography and thallium-201 tomography | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 6606353 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25450/1/0000900.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9149(83)90598-2 | en_US |
dc.identifier.source | The American Journal of Cardiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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