Hemodynamic determinants of exercise-induced ST-Segment depression in children with valvar aortic stenosis
dc.contributor.author | Kveselis, Daniel A. | en_US |
dc.contributor.author | Rocchini, Albert P. | en_US |
dc.contributor.author | Rosenthal, Amnon | en_US |
dc.contributor.author | Crowley, Dennis C. | en_US |
dc.contributor.author | Dick, Macdonald II | en_US |
dc.contributor.author | Snider, A. Rebecca | en_US |
dc.contributor.author | Moorehead, Catherine P. | en_US |
dc.date.accessioned | 2006-04-07T19:06:37Z | |
dc.date.available | 2006-04-07T19:06:37Z | |
dc.date.issued | 1985-04-15 | en_US |
dc.identifier.citation | Kveselis, Daniel A., Rocchini, Albert P., Rosenthal, Amnon, Crowley, Dennis C., Dick, MacDonald, Snider, A. Rebecca, Moorehead, Catherine (1985/04/15)."Hemodynamic determinants of exercise-induced ST-Segment depression in children with valvar aortic stenosis." The American Journal of Cardiology 55(9): 1133-1139. <http://hdl.handle.net/2027.42/25706> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T10-4C6CRKM-7N/2/eb0f8edb08e7ab850bc1ad5f128896c9 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25706 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3984890&dopt=citation | en_US |
dc.description.abstract | To evaluate the hemodynamic factors associated with treadmill-induced ST-segment depression in children with valvar aortic stenosis, 12 patients (mean age 13 years) with ST-segment depression during treadmill exercise and 5 patients (mean age 13 years) without ST-segment depression during treadmill exercise underwent exercise testing during cardiac catheterization. The left ventricular (LV) systolic pressure and LV outflow tract gradient at rest (177 +/- 25 vs 138 +/- 8 mm Hg and 59 +/- 18 vs 23 +/- 7 mm Hg, respectively) and corresponding pressures during maximal supine exercise (248 +/-37 vs 189 +/- 17 mm Hg and 112 +/- 34 vs 52 +/- 14 mm Hg) were significantly greater (p 2 supply-demand ratio during maximal supine exercise was significantly less (6.4 +/- 2.7 vs 11.8 +/- 0.7; p 2 supply-demand ratio less than 11.0 was 100% sensitive and specific in predicting treadmill-induced ST-segment depression. These results suggest that although the development of ST-segment depression during treadmill exercise is related to LV systolic pressure and LV outflow gradient, its major hemodynamic determinant is the LV-02 supply-demand ratio. | en_US |
dc.format.extent | 662839 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Hemodynamic determinants of exercise-induced ST-Segment depression in children with valvar aortic stenosis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics and Communicable Diseases, Section of Pediatric Cardiology, C.S. Mott Children's Hospital, The University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 3984890 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25706/1/0000260.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9149(85)90650-2 | en_US |
dc.identifier.source | The American Journal of Cardiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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