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Effects of antidepressant withdrawal on the dexamethasone suppression test

dc.contributor.authorDilsaver, Steven C.en_US
dc.contributor.authorGreden, John F.en_US
dc.date.accessioned2006-04-07T19:09:22Z
dc.date.available2006-04-07T19:09:22Z
dc.date.issued1985-02en_US
dc.identifier.citationDilsaver, Steven C., Greden, John F. (1985/02)."Effects of antidepressant withdrawal on the dexamethasone suppression test." Psychiatry Research 14(2): 111-121. <http://hdl.handle.net/2027.42/25762>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TBV-45RCF50-1P/2/122ef0021eb12afd537c2d1fcd91a380en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25762
dc.description.abstractWithdrawal of antidepressant medications may be a source of variance in dexamethasone suppression test (DST) results. We investigated this issue retrospectively through the serial analysis of postdexamethasone plasma cortisol concentrations and clinical severity in 15 patients and 9 control subjects before, during, and after antidepressant withdrawal. Postdexamethasone cortisol concentrations were significantly higher during the antidepressant withdrawal phase. Drug-withdrawal subjects also had an increased frequency of DST nonsuppression. Recent withdrawal of antidepressants requires further study as a possible source of variance for hypothalamic-pituitary-adrenal measures.en_US
dc.format.extent733094 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEffects of antidepressant withdrawal on the dexamethasone suppression testen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumSenoir Research Track Resident, University of Michigan, Ann Arbor, USAen_US
dc.contributor.affiliationumProfessor of Physchiatry and Director, Clinical Studies Unit for Affective Disorders and Senoir Research Associate, Mental Health Research Institute, University of Michigan, Ann Arbor, MI, USAen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25762/1/0000323.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0165-1781(85)90055-1en_US
dc.identifier.sourcePsychiatry Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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