Postnatal development of beta-endorphin immunoreactivity in the medulla oblongata of rat
dc.contributor.author | Alessi, Norman E. | en_US |
dc.contributor.author | Khachaturian, Henry | en_US |
dc.date.accessioned | 2006-04-07T19:09:46Z | |
dc.date.available | 2006-04-07T19:09:46Z | |
dc.date.issued | 1985-02 | en_US |
dc.identifier.citation | Alessi, Norman E., Khachaturian, Henry (1985/02)."Postnatal development of beta-endorphin immunoreactivity in the medulla oblongata of rat." Neuropeptides 5(4-6): 473-476. <http://hdl.handle.net/2027.42/25771> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WNR-4C48CP3-HB/2/35772d246d330fa8aacd2694a7c43df0 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25771 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3158836&dopt=citation | en_US |
dc.description.abstract | Beta-endorphin (B-END) like immunoreactivity (i.r.) levels were measured by radioimmunoassay in the medulla oblongata of developing rats on postnatal ages P1-P42 at 7 day intervals, and in adult rats. From P1 to P42, B-END i.r. increased from 77.0 +/- 1.3 fm to 900.0 +/- 21.6 fm per medulla region (Mean +/- S.E.M.). Adult levels of B-END i.r. were 852.0 +/- 17.0 fm per medulla region. When B-END i.r. was determined per unit protein during this developmental period, a statistically significant change in levels was noted. B-END i.r. dropped from P1 to P7, and then increased from P7 to P14 (P<0.01). From P14 through adult, levels did not change significantly. Despite a "drop-out" in the observed immunostaining of B-END neurons in caudal medulla (perikarya in the nucleus tractus solitarius) at P21, radioimmunoassayable levels of this peptide remained constant from P21 through adult per unit protein. | en_US |
dc.format.extent | 304682 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Postnatal development of beta-endorphin immunoreactivity in the medulla oblongata of rat | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Mental Health Research Institute, University of Michigan, Ann Arbor, Michigan, USA 48105 | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Mental Health Research Institute, University of Michigan, Ann Arbor, Michigan, USA 48105 | en_US |
dc.identifier.pmid | 3158836 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25771/1/0000332.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0143-4179(85)90057-5 | en_US |
dc.identifier.source | Neuropeptides | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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