Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey
dc.contributor.author | Dores, Robert M. | en_US |
dc.contributor.author | Akil, Huda | en_US |
dc.date.accessioned | 2006-04-07T19:13:18Z | |
dc.date.available | 2006-04-07T19:13:18Z | |
dc.date.issued | 1985 | en_US |
dc.identifier.citation | Dores, Robert M., Akil, Huda (1985)."Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey." Peptides 6(Supplement 2): 143-148. <http://hdl.handle.net/2027.42/25852> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T0M-47T8W6M-D9/2/f75d06872aa21e871e20a51a213041b3 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25852 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2867528&dopt=citation | en_US |
dc.description.abstract | Analysis of an acid extract of the striatum of the rhesus monkey revealed that the molar ratio of dynorphin A(1-8)-sized material and dynorphin (A(1-17)-sized material is approximately 1:1. In addition, the molar ratios of the dynorphin A-related end products to both dynorphin B(1-13)-sized material and alpha-neo-endorphin-sized material were approximately 1:1. Fractionation of an acid extract of the substantia nigra by gel filtration and reverse phase HPLC revealed the following molar ratios for pro-dynorphin-related end products. The molar ratio of dynorphin A(1-8) to dynorphin A(1-17) is approximately 6:1. The molar ratios of dynorphin A-related end products to dynorphin B(1-13) and alpha-neo-endorphin were approximately 0.5 and 0.8, respectively. Comparisons between proteolytic processing patterns of pro-dynorphin in the striatum and the substantia nigra of the rhesus monkey are considered. In addition, comparisons between pro-dynorphin processing in the substantia nigra of the rhesus monkey and the substantia nigra of the rat [4] are discussed. | en_US |
dc.format.extent | 610886 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan, Mental Health Research Institute, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | University of Michigan, Mental Health Research Institute, Ann Arbor, MI 48109, USA | en_US |
dc.identifier.pmid | 2867528 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25852/1/0000415.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0196-9781(85)90147-0 | en_US |
dc.identifier.source | Peptides | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.