A novel and efficient synthesis of the naturally occurring nucleoside doridosine
dc.contributor.author | Chern, Ji-Wang | en_US |
dc.contributor.author | Townsend, Leroy B. | en_US |
dc.date.accessioned | 2006-04-07T19:16:31Z | |
dc.date.available | 2006-04-07T19:16:31Z | |
dc.date.issued | 1985 | en_US |
dc.identifier.citation | Chern, Ji-Wang, Townsend,, Leroy B. (1985)."A novel and efficient synthesis of the naturally occurring nucleoside doridosine." Tetrahedron Letters 26(52): 6419-6422. <http://hdl.handle.net/2027.42/25938> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6THS-42H2DKF-280/2/db18ae01f5f3cc84a94e4a2d52cc385b | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25938 | |
dc.description.abstract | 1-Methylisoguanosine was synthesized by a one-pot reaction involving a condensation of 5-amino-1-([beta]--ribofuranosyl)imidazole-4-carboxamide (1) with methyl isothiocyanate, treatment of the resulting thiourea derivative with DCC furnished 5-(3-methyl-1-ureido)-1-([beta]--ribofuranosyl)imidazole-4-carbonitrile (4) which was then annulated with ethanolic ammonia to furnish doridosine in a 68% yield from 1. | en_US |
dc.format.extent | 270193 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | A novel and efficient synthesis of the naturally occurring nucleoside doridosine | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Medicinal Chemistry, College of Pharmacy and Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1065 U.S.A. | en_US |
dc.contributor.affiliationum | Department of Medicinal Chemistry, College of Pharmacy and Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1065 U.S.A. | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25938/1/0000501.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/S0040-4039(00)99016-6 | en_US |
dc.identifier.source | Tetrahedron Letters | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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