Use of ipratropium bromide in asthma: Results of a multi-clinic study
dc.contributor.author | Storms, William W. | en_US |
dc.contributor.author | Bodman, Stephen F. | en_US |
dc.contributor.author | Nathan, Robert A. | en_US |
dc.contributor.author | Busse, William W. | en_US |
dc.contributor.author | Bush, Robert K. | en_US |
dc.contributor.author | Falliers, Constantine J. | en_US |
dc.contributor.author | O'Hollaren, John D. | en_US |
dc.contributor.author | Weg, John G. | en_US |
dc.date.accessioned | 2006-04-07T19:24:09Z | |
dc.date.available | 2006-04-07T19:24:09Z | |
dc.date.issued | 1986-11-14 | en_US |
dc.identifier.citation | Storms, William W., Bodman, Stephen F., Nathan, Robert A., Busse, William W., Bush, Robert K., Falliers, Constantine J., O'Hollaren, John D., Weg, John G. (1986/11/14)."Use of ipratropium bromide in asthma: Results of a multi-clinic study." The American Journal of Medicine 81(5, Supplement 1): 61-66. <http://hdl.handle.net/2027.42/25980> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TDC-4CHHS8V-V/2/fbdaf280531765416ce7058b8e82fb33 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25980 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2947462&dopt=citation | en_US |
dc.description.abstract | A multi-center, double-blind, 90-day study compared an ipratropium bromide metered-dose inhaler (40 [mu]g four times a day) with a metaproterenol metered-dose inhaler (1,500 [mu]g four times a day) in 164 patients with asthma; of the 144 patients who completed the study, 71 received ipratropium and 73 received metaproterenol. Our results suggest that both drugs were equally effective bronchodilators. Although the shape of the pulmonary function response curves suggested that ipratropium has different bronchodilator kinetics than metaproterenol (in that it has a slower onset of action and a more prolonged duration), comparison of the areas under the curves for the two drugs showed that there was no statistical difference between ipratropium or metaproterenol. The only significant side effects noted with ipratropium were cough and exacerbation of symptoms; no anticholinergic side effects were noted. | en_US |
dc.format.extent | 588537 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Use of ipratropium bromide in asthma: Results of a multi-clinic study | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Family Medicine and Primary Care | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Pulmonary and Critical Care Medicine Division, Department of Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationother | Allergy Associates, Colorado Springs, Colorado, USA | en_US |
dc.contributor.affiliationother | Allergy Associates, Colorado Springs, Colorado, USA | en_US |
dc.contributor.affiliationother | Allergy Associates, Colorado Springs, Colorado, USA | en_US |
dc.contributor.affiliationother | University of Wisconsin and the William S. Middleton Veterans Administration Hospital, Madison, Wisconsin, USA | en_US |
dc.contributor.affiliationother | University of Wisconsin and the William S. Middleton Veterans Administration Hospital, Madison, Wisconsin, USA | en_US |
dc.contributor.affiliationother | Allergy and Asthma Clinic, Denver, Colorado, USA | en_US |
dc.contributor.affiliationother | Portland Medical Center, Portland, Oregon, USA | en_US |
dc.identifier.pmid | 2947462 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25980/1/0000046.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9343(86)90464-X | en_US |
dc.identifier.source | The American Journal of Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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