Cushing's syndrome after treatment: Changes in cortisol and ACTH levels, and amelioration of the depressive syndrome
dc.contributor.author | Starkman, Monica N. | en_US |
dc.contributor.author | Schteingart, David E. | en_US |
dc.contributor.author | Schork, M. Anthony | en_US |
dc.date.accessioned | 2006-04-07T19:24:25Z | |
dc.date.available | 2006-04-07T19:24:25Z | |
dc.date.issued | 1986-11 | en_US |
dc.identifier.citation | Starkman, Monica N., Schteingart, David E., Schork, M. Anthony (1986/11)."Cushing's syndrome after treatment: Changes in cortisol and ACTH levels, and amelioration of the depressive syndrome." Psychiatry Research 19(3): 177-188. <http://hdl.handle.net/2027.42/25987> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TBV-46041TB-DV/2/ac4aa57214d74865480e1822c51a4d41 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25987 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3025905&dopt=citation | en_US |
dc.description.abstract | Twenty-three patients with pituitary adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome were studied before and after treatment. The relationship between the amelioration of the depressive syndrome and changes in cortisol and ACTH levels was investigated. There was a significant difference in mean change in 24-hour urinary free cortisol (UFC) excretion for changes in the depressed mood score from first to last visit. There were also significant correlations between decreases in UFC and decreases in both the depressed mood score and the modified Hamilton depression score. These relationships were not found for ACTH. Furthermore, with cortisol decreased to normal levels, continued high ACTH levels did not prevent improvement in depressed mood. The possibility that cortisol may also play a role in the pathogenesis and/or maintenance of the mood disorder in psychiatric patients is discussed. | en_US |
dc.format.extent | 935671 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Cushing's syndrome after treatment: Changes in cortisol and ACTH levels, and amelioration of the depressive syndrome | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Psychiatry, School of Public Health, University of Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, School of Public Health, University of Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Biostatistics, School of Public Health, University of Michigan, USA | en_US |
dc.identifier.pmid | 3025905 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25987/1/0000053.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0165-1781(86)90096-X | en_US |
dc.identifier.source | Psychiatry Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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