Intermittent, ambulatory dobutamine infusions in patients with severe congestive heart failure
dc.contributor.author | Krell, Mark J. | en_US |
dc.contributor.author | Kline, Eva M. | en_US |
dc.contributor.author | Bates, Eric R. | en_US |
dc.contributor.author | Hodgson, John Mc B. | en_US |
dc.contributor.author | Dilworth, Lee R. | en_US |
dc.contributor.author | Laufer, Nathan | en_US |
dc.contributor.author | Vogel, Robert A. | en_US |
dc.contributor.author | Pitt, Bertram | en_US |
dc.date.accessioned | 2006-04-07T19:26:08Z | |
dc.date.available | 2006-04-07T19:26:08Z | |
dc.date.issued | 1986-10 | en_US |
dc.identifier.citation | Krell, Mark J., Kline, Eva M., Bates, Eric R., Hodgson, John McB., Dilworth, Lee R., Laufer, Nathan, Vogel, Robert A., Pitt, Bertram (1986/10)."Intermittent, ambulatory dobutamine infusions in patients with severe congestive heart failure." American Heart Journal 112(4): 787-791. <http://hdl.handle.net/2027.42/26035> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6W9H-4BT895K-27/2/23567e24f4b6adfb1ff021a5d45d2e0a | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26035 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3766379&dopt=citation | en_US |
dc.description.abstract | Thirteen ambulatory patients with severe congestive heart failure were treated with weekly outpatient 48-hour infusions of dobutamine. All 13 patients had at least a 25% increase in cardiac output during initial dobutamine titration, with a corresponding improvement in systemic vascular resistance. Improvement in functional class was achieved in only seven patients. Additionally, only three patients survived the 26-week study period. Although no change in ventricular ectopy was noted during the initial dobutamine infusions, six patients experienced sudden death; three other patients died of progressive heart failure and one died from pulmonary embolism. These data suggest that chronic intermittent ambulatory dobutamine infusions are only partly successful in improving symptoms and probably do not prolong survival in patients with severe congestive heart failure. Administration of this form of therapy on a clinical basis should be undertaken cautiously until safety and efficacy are demonstrated in prospective, controlled trials. | en_US |
dc.format.extent | 539950 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Intermittent, ambulatory dobutamine infusions in patients with severe congestive heart failure | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA; Veterans Administration Medical Center, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.contributor.affiliationum | Veterans Administration Medical Center, Ann Arbor, Mich., USA; Division of Cardiology, Department of Internal Medicine, University Hospital, University of Michigan, Ann Arbor, Mich., USA. | en_US |
dc.identifier.pmid | 3766379 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26035/1/0000108.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-8703(86)90475-8 | en_US |
dc.identifier.source | American Heart Journal | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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