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Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate

dc.contributor.authorKoek, Wouteren_US
dc.contributor.authorWoods, James H.en_US
dc.contributor.authorOrnstein, Paulen_US
dc.date.accessioned2006-04-07T19:26:29Z
dc.date.available2006-04-07T19:26:29Z
dc.date.issued1986-09-15en_US
dc.identifier.citationKoek, Wouter, Woods, James H., Ornstein, Paul (1986/09/15)."Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate." Life Sciences 39(11): 973-978. <http://hdl.handle.net/2027.42/26045>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T99-4754DFX-1TW/2/4c06ca360887631dd1c30016c90355d2en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26045
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2875374&dopt=citationen_US
dc.description.abstractA selective N-methyl-D-aspartate antagonist, DL-2-amino-5-phosphonovalerate, was found to produce PCP-like catalepsy, discriminative stimulus effects, and stereotyped operant responding in pigeons when administered intramuscularly. These results support the hypothesis that the behavioral effects of PCP-like drugs result at least in part from reduced neurotransmission at excitatory amino acid synapses utilizing N-methyl-D-aspartate preferring receptors.en_US
dc.format.extent352079 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titlePhencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerateen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology (W.K., J.H.W.) and Department of Psychology (J.H.W.), M6322 Medical Science Building I, University of Michigan, Ann Arbor, Michigan 48109-0010, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology (W.K., J.H.W.) and Department of Psychology (J.H.W.), M6322 Medical Science Building I, University of Michigan, Ann Arbor, Michigan 48109-0010, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology (W.K., J.H.W.) and Department of Psychology (J.H.W.), M6322 Medical Science Building I, University of Michigan, Ann Arbor, Michigan 48109-0010, USAen_US
dc.identifier.pmid2875374en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26045/1/0000118.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0024-3205(86)90285-7en_US
dc.identifier.sourceLife Sciencesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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