Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate
dc.contributor.author | Koek, Wouter | en_US |
dc.contributor.author | Woods, James H. | en_US |
dc.contributor.author | Ornstein, Paul | en_US |
dc.date.accessioned | 2006-04-07T19:26:29Z | |
dc.date.available | 2006-04-07T19:26:29Z | |
dc.date.issued | 1986-09-15 | en_US |
dc.identifier.citation | Koek, Wouter, Woods, James H., Ornstein, Paul (1986/09/15)."Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate." Life Sciences 39(11): 973-978. <http://hdl.handle.net/2027.42/26045> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T99-4754DFX-1TW/2/4c06ca360887631dd1c30016c90355d2 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26045 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2875374&dopt=citation | en_US |
dc.description.abstract | A selective N-methyl-D-aspartate antagonist, DL-2-amino-5-phosphonovalerate, was found to produce PCP-like catalepsy, discriminative stimulus effects, and stereotyped operant responding in pigeons when administered intramuscularly. These results support the hypothesis that the behavioral effects of PCP-like drugs result at least in part from reduced neurotransmission at excitatory amino acid synapses utilizing N-methyl-D-aspartate preferring receptors. | en_US |
dc.format.extent | 352079 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pharmacology (W.K., J.H.W.) and Department of Psychology (J.H.W.), M6322 Medical Science Building I, University of Michigan, Ann Arbor, Michigan 48109-0010, USA | en_US |
dc.contributor.affiliationum | Department of Pharmacology (W.K., J.H.W.) and Department of Psychology (J.H.W.), M6322 Medical Science Building I, University of Michigan, Ann Arbor, Michigan 48109-0010, USA | en_US |
dc.contributor.affiliationum | Department of Pharmacology (W.K., J.H.W.) and Department of Psychology (J.H.W.), M6322 Medical Science Building I, University of Michigan, Ann Arbor, Michigan 48109-0010, USA | en_US |
dc.identifier.pmid | 2875374 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26045/1/0000118.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0024-3205(86)90285-7 | en_US |
dc.identifier.source | Life Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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