Rapid expression of novel proteins in goldfish retina following optic nerve crush
dc.contributor.author | Cauley, Keith A. | en_US |
dc.contributor.author | Sherman, Thomas G. | en_US |
dc.contributor.author | Ford-Holevinski, Thomas S. | en_US |
dc.contributor.author | Agranoff, Bernard W. | en_US |
dc.date.accessioned | 2006-04-07T19:27:30Z | |
dc.date.available | 2006-04-07T19:27:30Z | |
dc.date.issued | 1986-08-14 | en_US |
dc.identifier.citation | Cauley, Keith A., Sherman, Thomas G., Ford-Holevinski, Thomas, Agranoff, Bernard W. (1986/08/14)."Rapid expression of novel proteins in goldfish retina following optic nerve crush." Biochemical and Biophysical Research Communications 138(3): 1177-1183. <http://hdl.handle.net/2027.42/26074> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WBK-4FW0C1P-2P/2/d8cac5e10dcff75f26045763b768a5ad | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26074 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3753493&dopt=citation | en_US |
dc.description.abstract | SummaryPolyadenylated messenger RNA was isolated from goldfish retinas at various times following unilateral crush of the optic nerve. RNA was translated in a cell-free system and product proteins analyzed by two-dimensional gel electrophoresis and autofluorography. Poly (A)+ mRNA-directed protein synthesis revealed an 8-fold increase in the labeling of polypeptides of about 30 kd Mr and a pI of 5.5 in retinas 2 d following optic nerve crush, compared with control retina mRNA translation products. In vitro labeling of retinal proteins revealed the enhanced synthesis of comparable 30 kd proteins in 2 d post-crush retinas. Evidence presented suggests that this 30 kd protein cluster may correspond to fish 30 kd stress or heat-shock proteins (hsp-30). | en_US |
dc.format.extent | 2710986 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Rapid expression of novel proteins in goldfish retina following optic nerve crush | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109-1687, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109-1687, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109-1687, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109-1687, USA | en_US |
dc.identifier.pmid | 3753493 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26074/1/0000148.pdf | en_US |
dc.identifier.source | Biochemical and Biophysical Research Communications | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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