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A tail withdrawal procedure for assessing analgesic activity in rhesus monkeys

dc.contributor.authorDykstra, Linda A.en_US
dc.contributor.authorWoods, James H.en_US
dc.date.accessioned2006-04-07T19:30:20Z
dc.date.available2006-04-07T19:30:20Z
dc.date.issued1986-06en_US
dc.identifier.citationDykstra, Linda A., Woods, James H. (1986/06)."A tail withdrawal procedure for assessing analgesic activity in rhesus monkeys." Journal of Pharmacological Methods 15(3): 263-269. <http://hdl.handle.net/2027.42/26151>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B73F9-477XP6F-RT/2/4b135f69b5c3ff100f373d8361f620cben_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26151
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3713205&dopt=citationen_US
dc.description.abstractRhesus monkeys were restrained in chairs from which their tails hung free so that their tails could be immersed into a thermos of water. Monkeys consistently kept their tails in 38-40[deg]C water for at least 20 sec, but withdrew them from 55[deg]C water in 1-4 sec. Tail withdrawal latencies from 55[deg]C water remained consistent over a period of 3 hr. Morphine produced dose-dependent increases in tail withdrawal latencies from 55[deg]C water, whereas pentobarbital, haloperidol, and phencyclidine did not increase tail withdrawal latencies except at doses that produced marked sedation.en_US
dc.format.extent408347 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleA tail withdrawal procedure for assessing analgesic activity in rhesus monkeysen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.identifier.pmid3713205en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26151/1/0000228.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0160-5402(86)90056-2en_US
dc.identifier.sourceJournal of Pharmacological Methodsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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