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1,1'-trimethylenebisthymine as synthetic model of dinucleotide TpT Electrochemical reduction

dc.contributor.authorMalinski, Tadeuszen_US
dc.contributor.authorLanger, Jerzy J.en_US
dc.contributor.authorMoiroux, Jacquesen_US
dc.contributor.authorElving, Philip Juliberen_US
dc.date.accessioned2006-04-07T19:31:43Z
dc.date.available2006-04-07T19:31:43Z
dc.date.issued1986-04-25en_US
dc.identifier.citationMalinski, Tadeusz, Langer, Jerzy J., Moiroux, Jacques, Elving, Philip J. (1986/04/25)."1,1'-trimethylenebisthymine as synthetic model of dinucleotide TpT Electrochemical reduction." Journal of Electroanalytical Chemistry 201(2): 329-345. <http://hdl.handle.net/2027.42/26190>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TGB-44YXMJH-DG/2/b72279694ba96d28f66881f023389a11en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26190
dc.description.abstractThe electrochemical reduction of 1,1'-trimethylenebisthymine (Thy(C3)Thy) in dimethylsulfoxide was investigated using dc polarography, cyclic voltammetry, controlled potential electrolysis and spectroelectrochemistry. Thy(C3)Thy is reduced in a two-election step (E1/2 = -2.40 V) to a diradical dianion which abstracts protons from the parent Thy(C3)Thy to form a neutral free diradical and the Thy(C3)Thy dianion. The neutral free diradical is further reduced and protonated to form 1,1'-trimethylenebisdihydrothymine. The dianion forms insoluble mercury salts producing up to three oxidation peaks (Epa between -0.35 and -0.07V). The effect of added base on the electrochemical and spectroelectrochemical behavior is described. The number of layers of the mercury- Thy(C3)Thy salt adsorbed in the anodic and stripped in the cathodic processes was calculated. The mechanism of adsorption is discussed.en_US
dc.format.extent1044318 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.title1,1'-trimethylenebisthymine as synthetic model of dinucleotide TpT Electrochemical reductionen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109 U.S.A.en_US
dc.contributor.affiliationotherDepartment of Chemistry, Oakland University, Rochester, MI 48063 U.S.A.en_US
dc.contributor.affiliationotherDepartment of Chemistry, Oakland University, Rochester, MI 48063 U.S.A.en_US
dc.contributor.affiliationotherLab. Chimie Analitique, U.A. C.N.R.S. No. 484, Fac. Pharmacie, Université Paris V, 4 Ave. Observatoire, 75270 Paris Cedex 06 Franceen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26190/1/0000269.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-0728(86)80058-4en_US
dc.identifier.sourceJournal of Electroanalytical Chemistryen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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