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Madin-Darby canine kidney cells display type I and type II insulin-like growth factor (IGF) receptors
dc.contributor.authorKrett, Nancy L.en_US
dc.contributor.authorHeaton, Joanne H.en_US
dc.contributor.authorGelehrter, Thomas D.en_US
dc.date.accessioned2006-04-07T19:35:45Z
dc.date.available2006-04-07T19:35:45Z
dc.date.issued1986-01-14en_US
dc.identifier.citationKrett, Nancy L., Heaton, Joanne H., Gelehrter, Thomas D. (1986/01/14)."Madin-Darby canine kidney cells display type I and type II insulin-like growth factor (IGF) receptors." Biochemical and Biophysical Research Communications 134(1): 120-127. <http://hdl.handle.net/2027.42/26301>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4F031HH-1BX/2/b28c88712a7497a05932db67a0bb23feen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26301
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3004425&dopt=citationen_US
dc.description.abstractUsing affinity cross-linking techniques, we report the presence of type I IGF and type II IGF receptors in Madin-Darby canine kidney cells, a line of cells lacking insulin receptors. The IGF receptors were further characterized by competition binding studies and found to be similar to IGF receptors in other tissue types. In Madin-Darby canine kidney cells, the type I IGF receptor binds IGF-I &gt; IGF-II &gt; insulin and the type II IGF receptor binds IGF-II and IGF-I with approximately the same affinity, but does not bind insulin.en_US
dc.format.extent582630 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleMadin-Darby canine kidney cells display type I and type II insulin-like growth factor (IGF) receptorsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Internal Medicine University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Human Genetics University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Internal Medicine University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Human Genetics University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Internal Medicine University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Human Genetics University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.identifier.pmid3004425en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26301/1/0000386.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(86)90535-8en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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