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Adrenergic and dopaminergic control of the canine paw microcirculation
dc.contributor.authorEndean, Eric D.en_US
dc.contributor.authorMukhopadhyay, Sunil K.en_US
dc.contributor.authorFung, Lit K.en_US
dc.contributor.authorCronenwett, Jack L.en_US
dc.contributor.authorStanley, James C.en_US
dc.contributor.authorLindenauer, S. Martinen_US
dc.date.accessioned2006-04-07T19:36:48Z
dc.date.available2006-04-07T19:36:48Z
dc.date.issued1986-01en_US
dc.identifier.citationEndean, Eric D., Mukhopadhyay, Sunil K., Fung, Lit K., Cronenwett, Jack L., Stanley, James C., Lindenauer, S. Martin (1986/01)."Adrenergic and dopaminergic control of the canine paw microcirculation." Journal of Surgical Research 40(1): 49-54. <http://hdl.handle.net/2027.42/26330>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WM6-4BNMR3X-1K/2/2e80b931b36b64b06bbd99f89e7aea78en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26330
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3941551&dopt=citationen_US
dc.description.abstractBasal isolated canine paw blood flow was equally distributed between arteriovenous anastomosis (AVA) and capillary circulations. Norepinephrine decreased AVA flow by 92% and capillary flow by 41%. Dopamine significantly reduced AVA flow by 94% compared to baseline with a 37% reduction in capillary flow. However, with [alpha]-adrenergic blockade dopamine decreased AVA flow 66% while capillary flow increased 42%. Isoproterenol increased capillary flow almost twofold and appeared to decrease AVA flow, although the latter was statistically insignificant. Differential effects of adrenergic and dopaminergic agonists on canine paw AVA and capillary blood flow suggest the existence of independent regulation of these components of the microcirculation.en_US
dc.format.extent560078 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleAdrenergic and dopaminergic control of the canine paw microcirculationen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelSurgery and Anesthesiologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Surgery, Division of Peripheral Vascular Surgery, University of Michigan, and Peripheral Vascular Research Laboratory, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Division of Peripheral Vascular Surgery, University of Michigan, and Peripheral Vascular Research Laboratory, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Division of Peripheral Vascular Surgery, University of Michigan, and Peripheral Vascular Research Laboratory, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Division of Peripheral Vascular Surgery, University of Michigan, and Peripheral Vascular Research Laboratory, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Division of Peripheral Vascular Surgery, University of Michigan, and Peripheral Vascular Research Laboratory, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Division of Peripheral Vascular Surgery, University of Michigan, and Peripheral Vascular Research Laboratory, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid3941551en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26330/1/0000417.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0022-4804(86)90144-7en_US
dc.identifier.sourceJournal of Surgical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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