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Endogenous pyrogen/interleukin-1 production in aged rats
dc.contributor.authorKauffman, Carol A.en_US
dc.date.accessioned2006-04-07T19:37:09Z
dc.date.available2006-04-07T19:37:09Z
dc.date.issued1986en_US
dc.identifier.citationKauffman, Carol A. (1986)."Endogenous pyrogen/interleukin-1 production in aged rats." Experimental Gerontology 21(2): 75-78. <http://hdl.handle.net/2027.42/26340>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T6J-47RJ3DH-1FS/2/22ca080b4b2b2800a3db897b69204a42en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26340
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3489633&dopt=citationen_US
dc.description.abstractThe effect of aging on the ability of macrophages to produce endogenous pyrogen/interleukin-1 (EP/IL-1) was tested in 13 young adult (2-3 mo) and 13 aged (24-26 mo) Fischer rats using a febrile response assay. Peritoneal macrophages from aged rats produced EP/IL-1 as well as young adult rats. Decreased production of EP/IL-1 does not appear to explain the diminished febrile response seen in the elderly.en_US
dc.format.extent199066 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEndogenous pyrogen/interleukin-1 production in aged ratsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeriatricsen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Infectious Diseases, Department Of Internal Medicine, Veterans Administration Medical Center, Ann Arbor, Michigan 48109, USA; University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.en_US
dc.identifier.pmid3489633en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26340/1/0000427.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0531-5565(86)90055-0en_US
dc.identifier.sourceExperimental Gerontologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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