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Insulin stimulated protein phosphorylation in human plasma liver membranes: Detection of endogenous or plasma membrane associated substrates for insulin receptor kinase
dc.contributor.authorCaro, Jose F.en_US
dc.contributor.authorShafer, Jules A.en_US
dc.contributor.authorTaylor, Simeon I.en_US
dc.contributor.authorRaju, S. M.en_US
dc.contributor.authorPerrotti, Nicholaen_US
dc.contributor.authorSinha, Madhur K.en_US
dc.date.accessioned2006-04-07T19:44:21Z
dc.date.available2006-04-07T19:44:21Z
dc.date.issued1987-12-31en_US
dc.identifier.citationCaro, JoseF., Shafer, Jules A., Taylor, Simeon I., Raju, S. M., Perrotti, Nichola, Sinha, Madhur K. (1987/12/31)."Insulin stimulated protein phosphorylation in human plasma liver membranes: Detection of endogenous or plasma membrane associated substrates for insulin receptor kinase." Biochemical and Biophysical Research Communications 149(3): 1008-1016. <http://hdl.handle.net/2027.42/26468>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DXRY44-260/2/cfc48670ecf848c6ec6c6c9d81afb0aaen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26468
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3322283&dopt=citationen_US
dc.description.abstractThe present work discloses a procedure for preparation of human liver plasma membranes containing catalytically competent insulin receptor kinase. In addition to insulin promoted phosphorylation of the [beta]-subunit of insulin receptor kinase, insulin promoted phosphorylation of pp120 and two other new proteins was demonstrated. The new proteins with molecular weights of 50,000 and 120,000 do not bind to WGA, pp120 antibody or insulin receptor antibody, but bind to the antiphosphotyrosyl antibody. The identity and physiological significance of these putative substrates for insulin receptor kinase remains to be established.en_US
dc.format.extent1209450 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleInsulin stimulated protein phosphorylation in human plasma liver membranes: Detection of endogenous or plasma membrane associated substrates for insulin receptor kinaseen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Diabetes Branch, National Institutes of Health, Bethesda, Maryland 20892, USA; Department of Medicine, School of Medicine, East Carolina University, Greenville, North Carolina 27858-4354, USA.en_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Diabetes Branch, National Institutes of Health, Bethesda, Maryland 20892, USA; Department of Medicine, School of Medicine, East Carolina University, Greenville, North Carolina 27858-4354, USA.en_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Diabetes Branch, National Institutes of Health, Bethesda, Maryland 20892, USA; Department of Medicine, School of Medicine, East Carolina University, Greenville, North Carolina 27858-4354, USA.en_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Diabetes Branch, National Institutes of Health, Bethesda, Maryland 20892, USA; Department of Medicine, School of Medicine, East Carolina University, Greenville, North Carolina 27858-4354, USA.en_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Diabetes Branch, National Institutes of Health, Bethesda, Maryland 20892, USA; Department of Medicine, School of Medicine, East Carolina University, Greenville, North Carolina 27858-4354, USA.en_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Diabetes Branch, National Institutes of Health, Bethesda, Maryland 20892, USA; Department of Medicine, School of Medicine, East Carolina University, Greenville, North Carolina 27858-4354, USA.en_US
dc.identifier.pmid3322283en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26468/1/0000003.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(87)90509-2en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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