Nucleotide sequences of the PA and PB1 genes of B/Ann Arbor/1/66 virus: comparison with genes of B/Lee/40 and type A influenza viruses
dc.contributor.author | DeBorde, Dan C. | en_US |
dc.contributor.author | Naeve, Clayton W. | en_US |
dc.contributor.author | Louise Herlocher, M. | en_US |
dc.contributor.author | Maassab, Hunein F. | en_US |
dc.date.accessioned | 2006-04-07T19:51:03Z | |
dc.date.available | 2006-04-07T19:51:03Z | |
dc.date.issued | 1987-07 | en_US |
dc.identifier.citation | DeBorde, Dan C., Naeve, Clayton W., Louise Herlocher, M., Maassab, Hunein F. (1987/07)."Nucleotide sequences of the PA and PB1 genes of B/Ann Arbor/1/66 virus: comparison with genes of B/Lee/40 and type A influenza viruses." Virus Research 8(1): 33-41. <http://hdl.handle.net/2027.42/26645> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T32-476RK2N-XF/2/2cb9bfd74e277f3b863e845027efd3e8 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26645 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3660943&dopt=citation | en_US |
dc.description.abstract | The complete sequences of the PA and PB1 genome RNA segments of B/Ann Arbor/1/66 virus have been determined. The PA vRNA is 2308 bases long. Its complementary RNA has a single open reading frame of 2187 bases, capable of encoding a PA protein of 726 amino acids with a molecular weight of 83,175 Da. The predicted PA polypeptide has an overall net charge of -- 7.5 at pH 7.0. The PB1 vRNA is 2369 bases long. Its complementary RNA has a single open reading frame of 2277 bases, capable of encoding a PB1 protein of 752 amino acids with a molecular weight of 84,332 Da. The predicted PB1 polypeptide has an overall net charge of + 18.5 at pH 7.0. Sequence homology comparisons of the PA and PB1 polypeptides from B/Ann Arbor/1/66 virus to the PA and PB1 polypeptides of type A influenza virus reveal respective homologies of approximately 38 and 60%. This high cross-type homology (61%) was previously reported for the PB1 protein of B/Lee/40 virus (Kemdirim et al., 1986). The cross-type homology for the PA protein is similar to that of other non-polymerase proteins, but is substantially lower than that seen for the PB1 protein. Thus, the high cross-type homology that exists for the PB1 gene does not appear to be a characteristic of all polymerase genes. | en_US |
dc.format.extent | 767768 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Nucleotide sequences of the PA and PB1 genes of B/Ann Arbor/1/66 virus: comparison with genes of B/Lee/40 and type A influenza viruses | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Virology and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, U.S.A. | en_US |
dc.identifier.pmid | 3660943 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26645/1/0000187.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0168-1702(87)90038-4 | en_US |
dc.identifier.source | Virus Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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