Topological characterization of the simian virus 40 transcription complex
dc.contributor.author | Petryniak, Bronislawa | en_US |
dc.contributor.author | Lutter, Leonard C. | en_US |
dc.date.accessioned | 2006-04-07T19:58:02Z | |
dc.date.available | 2006-04-07T19:58:02Z | |
dc.date.issued | 1987-01-30 | en_US |
dc.identifier.citation | Petryniak, Bronislawa, Lutter, Leonard C. (1987/01/30)."Topological characterization of the simian virus 40 transcription complex." Cell 48(2): 289-295. <http://hdl.handle.net/2027.42/26833> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WSN-4C58VYW-J/2/405d554b8ae86467959815dadae9144f | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26833 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3026641&dopt=citation | en_US |
dc.description.abstract | We have used sedimentation analysis as well as agarose gel electrophoresis to characterize the topological state of the DNA of the Simian Virus 40 (SV40) transcription complex. We found that the complex DNA contained constrained topological tension, presumably resulting from nucleosome-like structures, but no detectable unconstrained (i.e., relaxable) topological tension. These results contradict previous conclusions that the SV40 transcription complex contains only unconstrained topological tension. Our findings are also the opposite of what has been proposed to be the case for the 5S gene analyzed in Xenopus oocytes. Thus the proposal that expression from the 5S gene is associated with substantial topological tension is not valid for expression from the SV40 late gene. | en_US |
dc.format.extent | 2071618 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Topological characterization of the simian virus 40 transcription complex | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry The University of Michigan Medical School, Ann Arbor, Michigan 48109-0606, USA | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry The University of Michigan Medical School, Ann Arbor, Michigan 48109-0606, USA | en_US |
dc.identifier.pmid | 3026641 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26833/1/0000393.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0092-8674(87)90432-6 | en_US |
dc.identifier.source | Cell | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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