Hypothermic cardiopulmonary bypass: A comparison between alpha and pH stat regulation in the dog
dc.contributor.author | Bove, Edward L. | en_US |
dc.contributor.author | West, Howard L. | en_US |
dc.contributor.author | Paskanik, Andrew M. | en_US |
dc.date.accessioned | 2006-04-07T19:59:26Z | |
dc.date.available | 2006-04-07T19:59:26Z | |
dc.date.issued | 1987-01 | en_US |
dc.identifier.citation | Bove, Edward L., West, Howard L., Paskanik, Andrew M. (1987/01)."Hypothermic cardiopulmonary bypass: A comparison between alpha and pH stat regulation in the dog." Journal of Surgical Research 42(1): 66-73. <http://hdl.handle.net/2027.42/26870> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WM6-4BNDXY8-VK/2/3169d3809c7fc246fb07fa893fe65941 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26870 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3100868&dopt=citation | en_US |
dc.description.abstract | The accepted normal pH of 7.40 may not be optimal at lower temperatures. This study evaluated the effect of maintaining pH in the accepted normal range at hypothermia (group 1, pH stat) or at normothermia (group 2, alpha stat) on organ blood flow and hemodynamics in dogs. The desired pH was achieved at all temperatures by adjusting pCO2. Hypothermia to 20[deg]C was induced by high flow bypass in both groups followed by 45 min of reduced flow before rewarming. In group 1 (n = 10), pH was 7.45 +/- 0.02 at 20[deg]C and in group 2 (n = 11) it was 7.64 +/- 0.01. A greater base excess developed by the end of the low flow period in pH stat animals (-9.4 +/- 1.1 vs -2.8 +/- 0.8, P P P P P P P P pCO2 control between alpha and pH stat regulation assume lesser importance for regional blood flow when normal systemic flow is maintained during cooling and rewarming. | en_US |
dc.format.extent | 677703 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Hypothermic cardiopulmonary bypass: A comparison between alpha and pH stat regulation in the dog | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Surgery, State University of New York Upstate Medical Center, Syracuse, New York, USA; University of Michigan Medical Center, Ann Arbor, Michigan, USA. | en_US |
dc.contributor.affiliationum | The University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, State University of New York Upstate Medical Center, Syracuse, New York, USA. | en_US |
dc.contributor.affiliationum | The University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, State University of New York Upstate Medical Center, Syracuse, New York, USA. | en_US |
dc.identifier.pmid | 3100868 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26870/1/0000435.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-4804(87)90067-9 | en_US |
dc.identifier.source | Journal of Surgical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.