Pheochromocytoma, polycythemia and venous thrombosis
dc.contributor.author | Shulkin, Barry L. | en_US |
dc.contributor.author | Shapiro, Brahm | en_US |
dc.contributor.author | Sisson, James C. | en_US |
dc.date.accessioned | 2006-04-07T20:04:07Z | |
dc.date.available | 2006-04-07T20:04:07Z | |
dc.date.issued | 1987-10 | en_US |
dc.identifier.citation | Shulkin, Barry L., Shapiro, Brahm, Sisson, James C. (1987/10)."Pheochromocytoma, polycythemia and venous thrombosis." The American Journal of Medicine 83(4): 773-776. <http://hdl.handle.net/2027.42/26991> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TDC-4CMYWS2-TM/2/6bdc121b1307d719a18ff3dbf002e62d | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26991 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3674065&dopt=citation | en_US |
dc.description.abstract | Polycythemia is rarely associated with pheochromocytoma. A patient with a 22-year history of malignant pheochromocytoma is presented in whom major complications developed as a result of long-standing polycythemia, apparently due to secretion of erythropoletin by the tumors. Despite attempts to reduce tumor burden by surgery, chemotherapy, and large doses of 1-131-metalodobenzyl guanidine, polycythemia persisted. Extensive venous thrombosis developed requiring hospitalization and anticoagulation. Thus, polycythemia itself may be a cause of major morbidity in patients with pheochromocytoma, and prophylactic measures may be warranted. Review of the 130 patients with benign and malignant pheochromocytoma studied since the introduction of I-131-metaiodobenzylguanidine in 1980 revealed another six patients with hematocrits over 50 but only one had a hematocrit greater than 55 and required regular phlebotomy. In contrast, anemia (hematocrit less than 35) due to variety of causes was present in 18 cases. | en_US |
dc.format.extent | 766792 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Pheochromocytoma, polycythemia and venous thrombosis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Family Medicine and Primary Care | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 3674065 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26991/1/0000558.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9343(87)90913-2 | en_US |
dc.identifier.source | The American Journal of Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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