Plasma postdexamethasone cortisol levels in schizoaffective disorder
dc.contributor.author | Meador-Woodruff, James H. | en_US |
dc.contributor.author | Greden, John F. | en_US |
dc.contributor.author | Grunhaus, Leon J. | en_US |
dc.contributor.author | Haskett, Roger F. | en_US |
dc.date.accessioned | 2006-04-07T20:10:19Z | |
dc.date.available | 2006-04-07T20:10:19Z | |
dc.date.issued | 1988-10 | en_US |
dc.identifier.citation | Meador-Woodruff, James H., Greden, John F., Grunhaus, Leon, Haskett, Roger F. (1988/10)."Plasma postdexamethasone cortisol levels in schizoaffective disorder." Psychiatry Research 26(1): 35-42. <http://hdl.handle.net/2027.42/27102> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TBV-4603H91-2K/2/35a1af9b9376055e26c12c43205111c3 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27102 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3237905&dopt=citation | en_US |
dc.description.abstract | The degree of hypothalamic-pituitary-adrenal (HPA) axis dysregulation in depressed patients with schizoaffective disorder was compared to that seen in patients with major depressive disorder with and without delusional features. The frequency of nonsuppression to dexamethasone was similar for all three diagnostic groups. Maximum postdexamethasone plasma cortisol was greater for delusional depressives, but did not differ between patients with major depressive and schizoaffective disorders. Modest correlations were found between postdexamethasone plasma cortisol levels, severity of illness, age, and recent weight loss, for patients with both major depressive disorder and delusional depression. For schizoaffective patients, associations between postdexamethasone plasma cortisol levels and various measures of severity of illness, but not age and recent weight loss, were found. Although HPA axis dysregulation occurs more frequently in all three of the studied diagnostic groups than in normal individuals, factors contributing to this dysregulation may be qualitatively different for schizoaffective patients. | en_US |
dc.format.extent | 657089 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Plasma postdexamethasone cortisol levels in schizoaffective disorder | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Clinical Studies Unit of the University of Michigan Depression Program, University of Michigan Medical Center, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Clinical Studies Unit of the University of Michigan Depression Program, University of Michigan Medical Center, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Clinical Studies Unit of the University of Michigan Depression Program, University of Michigan Medical Center, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Psychiatry, Clinical Studies Unit of the University of Michigan Depression Program, University of Michigan Medical Center, Ann Arbor, MI 48109, USA | en_US |
dc.identifier.pmid | 3237905 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27102/1/0000094.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0165-1781(88)90085-6 | en_US |
dc.identifier.source | Psychiatry Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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