Changes in somatosensory evoked potentials following an experimental focal ischaemic lesion in thalamus
dc.contributor.author | Ladds, A. | en_US |
dc.contributor.author | Branston, N. M. | en_US |
dc.contributor.author | Vajda, J. | en_US |
dc.contributor.author | McGillicuddy, John E. | en_US |
dc.contributor.author | Symon, L. | en_US |
dc.date.accessioned | 2006-04-07T20:19:35Z | |
dc.date.available | 2006-04-07T20:19:35Z | |
dc.date.issued | 1988 | en_US |
dc.identifier.citation | Ladds, A., Branston, N. M., Vajda, J., McGillicuddy, J. E., Symon, L. (1988)."Changes in somatosensory evoked potentials following an experimental focal ischaemic lesion in thalamus." Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section 71(3): 233-240. <http://hdl.handle.net/2027.42/27315> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYY-482XX48-1K/2/6dc423e626f6ff1b6284a4ee07733f1b | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27315 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2451605&dopt=citation | en_US |
dc.description.abstract | Experiments have been performed to produce localized thalamic ischaemia in baboons anaesthetised with alpha-chloralose. Somatosensory evoked potentials to median nerve stimulation were recorded in the medial lemniscus. VPL of thalamus and the primary somatosensory cortex. Local blood flow was also recorded by the hydrogen clearance technique in these regions. The early potential recorded in thalamus has been shown to be generated from 3 sources: (i) a positivity generated outside the VPL, (ii) local wavelets, most likely from synaptic activity close to the recording electrode, and (iii) a local overall negativity. The first of these potentials alone remains after thalamic ischaemia. It arises below the level of the thalamus, being very likely generated by the afferent volley in the medial lemniscus, and is seen in the surface-recorded response as the early component P8 (corresponding to P15 in the human). | en_US |
dc.format.extent | 578780 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Changes in somatosensory evoked potentials following an experimental focal ischaemic lesion in thalamus | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Section of Neurosurgery, The University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationother | Gough-Cooper Department of Neurological Surgery, Institute of Neurology, Queen Square, London WC1, U.K. | en_US |
dc.contributor.affiliationother | Gough-Cooper Department of Neurological Surgery, Institute of Neurology, Queen Square, London WC1, U.K. | en_US |
dc.contributor.affiliationother | National Institute of Neurosurgery, Amerikai 57, Budapest 1145, Hungary | en_US |
dc.contributor.affiliationother | Gough-Cooper Department of Neurological Surgery, Institute of Neurology, Queen Square, London WC1, U.K. | en_US |
dc.identifier.pmid | 2451605 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27315/1/0000336.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0168-5597(88)90008-1 | en_US |
dc.identifier.source | Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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