Cytochemical localization of Ca2+-ATPase activity in peripheral nerve
dc.contributor.author | Mata, Marina | en_US |
dc.contributor.author | Staple, Julie | en_US |
dc.contributor.author | Fink, David J. | en_US |
dc.date.accessioned | 2006-04-07T20:21:53Z | |
dc.date.available | 2006-04-07T20:21:53Z | |
dc.date.issued | 1988-03-29 | en_US |
dc.identifier.citation | Mata, Marina, Staple, Julie, Fink, David J. (1988/03/29)."Cytochemical localization of Ca2+-ATPase activity in peripheral nerve." Brain Research 445(1): 47-54. <http://hdl.handle.net/2027.42/27368> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYR-485CX7X-M/2/234d23ddc9e8a24c72d5867573a2ce10 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27368 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2966649&dopt=citation | en_US |
dc.description.abstract | We used an electron microscopic cytochemical method to determine the localization of Ca2+-ATPase in rat peripheral nerve. We found that reaction product occurred along most cytoplasmic membranes in the dorsal root ganglia (DRG). Unmyelinated axons demonstrated reaction product on the axolemma diffusely along their length. Myelinated fibers, in contrast, had reaction product limited to the axolema in the paranodal region. Internodal axolemma never showed reaction product and nodal axolemma was only occasionally stained, usually in sections reacted for the maximum times. Schwann cell plasma membranes uniformly showed reaction product. The restricted localization of Ca2+-ATPase to the paranodal region of myelinated fibers suggests that calcium efflux may occur principally at those sites. | en_US |
dc.format.extent | 1921681 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Cytochemical localization of Ca2+-ATPase activity in peripheral nerve | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Neurology Research Laboratory, University of Michigan and VA Medical Center, Ann Arbor, MI 48105, U.S.A. | en_US |
dc.contributor.affiliationum | Neurology Research Laboratory, University of Michigan and VA Medical Center, Ann Arbor, MI 48105, U.S.A. | en_US |
dc.contributor.affiliationum | Neurology Research Laboratory, University of Michigan and VA Medical Center, Ann Arbor, MI 48105, U.S.A. | en_US |
dc.identifier.pmid | 2966649 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27368/1/0000394.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0006-8993(88)91072-4 | en_US |
dc.identifier.source | Brain Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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