View Item 

Show simple item record

Chronic treatment with amitriptyline produces supersensitivity to nicotine,
dc.contributor.authorDilsaver, Steven C.en_US
dc.contributor.authorMajchrzak, Mark J.en_US
dc.contributor.authorAlessi, Norman E.en_US
dc.date.accessioned2006-04-07T20:25:22Z
dc.date.available2006-04-07T20:25:22Z
dc.date.issued1988-01-15en_US
dc.identifier.citationDilsaver, Steven C., Majchrzak, Mark J., Alessi, Norman E. (1988/01/15)."Chronic treatment with amitriptyline produces supersensitivity to nicotine,." Biological Psychiatry 23(2): 169-175. <http://hdl.handle.net/2027.42/27428>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T4S-482XF4W-82/2/841a57493087a5f135ded9f7b16b8134en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/27428
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3334885&dopt=citationen_US
dc.description.abstractThe authors used a thermoregulation paradigm to evaluate effects of amitriptyline (AMI) on the sensitivity of a nicotinic mechanism involved in the regulation of core temperature in rats. Treatment with this tricyclic was associated with a significant increase in the hypothermie response to nicotine. Supersensitivity persisted for a minimum of 7.5 days following the last dose of AMI, and a significant proportion of animals displayed increased sensitivity after 14.5 days of abstinence. Implications for the mechanism of action of AMI are highlighted.en_US
dc.format.extent563470 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleChronic treatment with amitriptyline produces supersensitivity to nicotine,en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMental Health Research Institute, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumMental Health Research Institute, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumMental Health Research Institute, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USAen_US
dc.identifier.pmid3334885en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/27428/1/0000466.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-3223(88)90087-Xen_US
dc.identifier.sourceBiological Psychiatryen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
0000466.pdf
Size:
550.2KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.